Association between right ventricular dysfunction and restrictive lung disease in childhood cancer survivors as measured by quantitative echocardiography
Patel A, Weismann C, Weiss P, Russell K, Bazzy‐Asaad A, Kadan‐Lottick N. Association between right ventricular dysfunction and restrictive lung disease in childhood cancer survivors as measured by quantitative echocardiography. Pediatric Blood & Cancer 2014, 61: 2059-2064. PMID: 25130668, DOI: 10.1002/pbc.25157.Peer-Reviewed Original ResearchConceptsRestrictive lung diseaseChildhood cancer survivorsLung diseaseCancer survivorsIsovolumetric accelerationRV dysfunctionRV functionVentricular dysfunctionMean ageTricuspid annular plane systolic excursionQuantitative echocardiographyAnnular plane systolic excursionEarly RV dysfunctionLower tissue DopplerRestrictive pulmonary impairmentSubclinical RV dysfunctionRight ventricular dysfunctionLeft ventricular dysfunctionPulmonary function testsRight ventricular functionParticipants' mean ageMeasures of contractilityLarger study populationLymphoma/leukemiaThoracic radiationEffect of vitamin D–binding protein genotype on the development of asthma in children
Navas-Nazario A, Li FY, Shabanova V, Weiss P, Cole DE, Carpenter TO, Bazzy-Asaad A. Effect of vitamin D–binding protein genotype on the development of asthma in children. Annals Of Allergy Asthma & Immunology 2014, 112: 519-524. PMID: 24745702, PMCID: PMC4070170, DOI: 10.1016/j.anai.2014.03.017.Peer-Reviewed Original ResearchMeSH KeywordsAsthmaChild, PreschoolCholestanetriol 26-MonooxygenaseConnecticutCytochrome P450 Family 2FemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHispanic or LatinoHumansInfantMalePolymorphism, Single NucleotideReceptors, CalcitriolRetrospective StudiesVitamin DVitamin D-Binding ProteinConceptsDevelopment of asthmaVitamin DGC genotypeVitamin D metabolite levelsRetrospective medical record reviewVitamin D insufficiencyMedical record reviewCurrent clinical dataSingle nucleotide polymorphismsVitamin D metabolitesGC single nucleotide polymorphismsHispanic populationPotential vitamin DMonths of ageD insufficiencyAsthma morbidityHealthy infantsRecord reviewD metabolitesHealthy childrenInflammatory diseasesNucleotide polymorphismsClinical dataProtective effectAsthma