Philip Corlett, PhD
Associate Professor of PsychiatryCards
About
Research
Publications
2025
A remote care navigation solution associated with improved utilization and outcomes of mental healthcare: A nationwide cohort study in the USA
Ward E, Hawrilenko M, Ambwani G, Brown M, Krystal J, Corlett P, Chekroud A. A remote care navigation solution associated with improved utilization and outcomes of mental healthcare: A nationwide cohort study in the USA. PLOS ONE 2025, 20: e0331454. PMID: 40966254, PMCID: PMC12445557, DOI: 10.1371/journal.pone.0331454.Peer-Reviewed Original ResearchConceptsCare navigationMental healthcare utilizationHealthcare utilizationCohort studyComplete demographic informationMental health benefitsMental health assessmentNationwide cohort studyAssociated with greater engagementMental healthcareCare utilizationRetrospective cohort studyPeople of colorScheduling appointmentsWhite participantsHealth assessmentCareGreater engagementParticipants of colorDemographic informationClinical implementationBaseline symptomsHealth benefitsParticipantsUS employersIdentifying individuals at clinical high risk for psychosis using a battery of tasks sensitive to symptom mechanisms
Williams T, Gold J, Waltz J, Schiffman J, Ellman L, Strauss G, Walker E, Woods S, Powers A, Kenney J, Pappu M, Corlett P, Tran T, Silverstein S, Zinbarg R, Mittal V. Identifying individuals at clinical high risk for psychosis using a battery of tasks sensitive to symptom mechanisms. Translational Psychiatry 2025, 15: 311. PMID: 40849429, PMCID: PMC12375010, DOI: 10.1038/s41398-025-03539-5.Peer-Reviewed Original ResearchConceptsCHR-P individualsClinical high riskCHR-PClinical InterviewComputerized assessmentAssessment of psychosis riskStructured Clinical InterviewRisk calculator scoresNeurocognitive mechanismsPsychosis symptomsPsychosis riskBehavioral tasksUnique predictorsMental disordersTask batteryPsychosisTask variablesComparison groupHealthy controlsRisk severityUpdate beliefsTaskMultinomial logistic regressionConsortium studyIndividualsMultisensory overweighting of perceptual priors relates to positive symptoms in individuals at clinical high risk of psychosis
Pokorny V, Ellman L, Strauss G, Walker E, Woods S, Powers A, Corlett P, Silverstein S, Waltz J, Gold J, Schiffman J, Mittal V. Multisensory overweighting of perceptual priors relates to positive symptoms in individuals at clinical high risk of psychosis. Journal Of Vision 2025, 25: 2130. DOI: 10.1167/jov.25.9.2130.Peer-Reviewed Original ResearchFunctional Correlates of Atypical Visuoperceptual Organization in a Multisite Clinical High-Risk Sample
Pokorny V, Tran T, Williams T, Kenney J, Silverstein S, Gold J, Waltz J, Schiffman J, Ellman L, Strauss G, Walker E, Woods S, Powers A, Corlett P, Mittal V. Functional Correlates of Atypical Visuoperceptual Organization in a Multisite Clinical High-Risk Sample. Journal Of Psychopathology And Clinical Science 2025, 134: 527-539. PMID: 40193439, PMCID: PMC12162206, DOI: 10.1037/abn0000992.Peer-Reviewed Original ResearchConceptsClinical high riskPsychotic-like Experiences groupClinical high-risk statusClinical high-risk samplesMeasures of cognitive abilityClinical high-risk groupHigh-risk sampleMeasuring perceptual organizationFaces taskPsychotic disordersPerceptual priorsCognitive abilitiesCognitive functionClinical groupsPerceptual organizationHealthy control groupContext-sensitiveSocial functioningTwo-tone imagesTarget circleSymbolic codeEbbinghausFunctional correlatesTaskParticipantsPseudosocial cognition and paranoia
Corlett P, Rossi-Goldthorpe R, Suthaharan P, Sheffield J, de Obeso S, Heyes C. Pseudosocial cognition and paranoia. Trends In Cognitive Sciences 2025 PMID: 40518352, DOI: 10.1016/j.tics.2025.05.019.Peer-Reviewed Original ResearchPrior Expectations of Volatility Following Psychotherapy for Delusions
Sheffield J, Sloan A, Corlett P, Rogers B, Vandekar S, Liu J, Beals K, Hall L, Gautier T, Moussa-Tooks A, Torregrossa L, Achee M, Armstrong K, Woodward N, Belt K, Freeman D, Isham L, Diamond R, Brinen A, Heckers S. Prior Expectations of Volatility Following Psychotherapy for Delusions. JAMA Network Open 2025, 8: e2517132. PMID: 40553472, PMCID: PMC12188364, DOI: 10.1001/jamanetworkopen.2025.17132.Peer-Reviewed Original ResearchConceptsDelusion severityPersecutory delusionsPrefrontal cortexBrain activityStandard careProbabilistic reversal learning taskPsychotic Symptom Rating ScalesCommunity mental health centerBlood oxygenation level-dependent signal changesFunctional magnetic resonance imagingRandomized clinical trialsReversal learning taskCognitive behavioral therapyModels of delusionsMental health centerBelief update taskSymptom Rating ScaleIntention-to-treat analysisCaudate activationAntipsychotic medicationAssociated with clinical improvementDelusional disorderSchizophrenia spectrumBehavioral therapyHealth centersIncreased face perception in individuals at clinical high-risk for psychosis: mechanisms, sex differences, and clinical correlates
Tran T, Keane B, Thompson J, Robinson B, Kenney J, Williams T, Waltz J, Levin J, Kafadar E, Gold J, Schiffman J, Ellman L, Walker E, Strauss G, Mittal V, Zinbarg R, Corlett P, Powers A, Woods S, Silverstein S. Increased face perception in individuals at clinical high-risk for psychosis: mechanisms, sex differences, and clinical correlates. Schizophrenia 2025, 11: 74. PMID: 40355455, PMCID: PMC12069608, DOI: 10.1038/s41537-025-00624-y.Peer-Reviewed Original ResearchClinical high riskCHR participantsCHR groupPhase of psychotic illnessAssessment of psychosis riskSevere positive symptomsGender of facesAssess response biasClinical correlatesPositive symptomsPsychiatric controlsPsychosis riskPsychotic illnessAccuracy of perceptionFace perceptionScrambled conditionPerceptual sensitivityPoorer roleResponse biasFace testPerceptual organizationComputerized assessmentSex differencesAltered visual perceptionPsychosis20 Years of Aberrant Salience in Psychosis: What Have We Learned?
Corlett P, Fraser K. 20 Years of Aberrant Salience in Psychosis: What Have We Learned? American Journal Of Psychiatry 2025, 182: 819-829. PMID: 40134268, DOI: 10.1176/appi.ajp.20240556.Peer-Reviewed Original ResearchDopamine systemComputational cognitive neuroscienceAberrant salienceDelusion formationDopamine dysfunctionDopaminergic circuitsSalience hypothesisCognitive neuroscienceNeurochemical dysfunctionBehavioral neuroscientistsClinical phenomenologyCogent theoryDopaminePsychosisNovel predictionsBehavioral lociDelusionsAttention of cliniciansContemporary theoriesBelief formationHallucinationsBeliefsNeuroscienceDysfunctionNeuroscientistsInterpersonal difficulties and suicidal ideation in young people at clinical high-risk for psychosis and help-seeking clinical controls
Bailey A, Bauer B, Mittal V, Ellman L, Strauss G, Walker E, Powers A, Kenney J, Corlett P, Woods S, Gold J, Schiffman J, Waltz J, Silverstein S. Interpersonal difficulties and suicidal ideation in young people at clinical high-risk for psychosis and help-seeking clinical controls. Psychiatry Research 2025, 348: 116467. PMID: 40184931, PMCID: PMC12051163, DOI: 10.1016/j.psychres.2025.116467.Peer-Reviewed Original ResearchConceptsRates of suicidal ideationPresence of suicidal ideationClinical high riskSuicidal ideationInterpersonal difficultiesMental health concernsInterpersonal traumaExperiences of suicidal ideationHelp-seeking controlsDSM-5 diagnosisSame-age peersDSM-5Interpersonal mechanismsDiagnostic groupsIdeationYoung peoplePsychosisClinical controlCHRPHealth concernHigh riskAssociated with presenceDifficultiesSuicideLogistic regression modelsA generalized reward processing deficit pathway to negative symptoms across diagnostic boundaries
Spilka M, Millman Z, Waltz J, Walker E, Levin J, Powers A, Corlett P, Schiffman J, Gold J, Silverstein S, Ellman L, Mittal V, Woods S, Zinbarg R, Strauss G. A generalized reward processing deficit pathway to negative symptoms across diagnostic boundaries. Psychological Medicine 2025, 55: e6. PMID: 39901872, PMCID: PMC11968125, DOI: 10.1017/s003329172400326x.Peer-Reviewed Original ResearchConceptsNegative symptomsDiagnostic boundariesPsychiatric diagnosisTransdiagnostic sample of youthProcessing profilesEffort-cost computationsPositive valence systemsElevated negative symptomsHelp-seeking participantsClinical high riskClinical group membershipSample of youthHedonic reactivityTransdiagnostic sampleCHR criteriaNeurobiological mechanismsPsychosis riskSubgroup of participantsBehavioral tasksClinical InterviewPsychiatric disordersClinical participantsValence systemsGroup membershipDiagnostic classification
Clinical Trials
Current Trials
Song-making In a Group (SING)
HIC ID2000026376RolePrincipal InvestigatorPrimary Completion Date08/31/2024Recruiting ParticipantsTeen Brain and Behavior Study
HIC ID1111009332RoleSub InvestigatorPrimary Completion Date12/21/2022Recruiting ParticipantsGenderBothAge13 years - 17 years
Academic Achievements & Community Involvement
News
News
- September 05, 2025Source: Scientific American
Newfound 'Reality Signal' Helps the Brain Tell Imagination from Real Life
- September 04, 2025Source: The American Journal of Psychiatry
20 Years of Aberrant Salience in Psychosis: What Have We Learned?
- December 17, 2024Source: Yale News
Paranoia May Be, In Part, a Visual Problem
- November 15, 2024
Corlett Speaks at 'Artificial Intelligence and Mental Health' Conference in Shanghai
Get In Touch
Contacts
Mailing Address
Psychiatry
34 Park St., CNRU
New Haven, CT 06519
United States