2010
Glutamatergic Model Psychoses: Prediction Error, Learning, and Inference
Corlett PR, Honey GD, Krystal JH, Fletcher PC. Glutamatergic Model Psychoses: Prediction Error, Learning, and Inference. Neuropsychopharmacology 2010, 36: 294-315. PMID: 20861831, PMCID: PMC3055519, DOI: 10.1038/npp.2010.163.Peer-Reviewed Original Research
2009
From drugs to deprivation: a Bayesian framework for understanding models of psychosis
Corlett PR, Frith CD, Fletcher PC. From drugs to deprivation: a Bayesian framework for understanding models of psychosis. Psychopharmacology 2009, 206: 515-530. PMID: 19475401, PMCID: PMC2755113, DOI: 10.1007/s00213-009-1561-0.Peer-Reviewed Original ResearchConceptsSymptoms of psychosisImportance of perceptionsProcessing of informationCognitive modelPrior expectanciesPerceptual AberrationModel of psychosisNeural circuitryInformation processingDifferent manipulationsPositive symptomsExperimental manipulationSerotonergic hallucinogensPerceptionPsychosisNew predictionsPsychotomimetic drugsUseful settingProcessingDistinctive effectsSymptomsInferenceNMDA receptor antagonistDistinct symptomsLearning
2007
From prediction error to psychosis: ketamine as a pharmacological model of delusions
Corlett PR, Honey GD, Fletcher PC. From prediction error to psychosis: ketamine as a pharmacological model of delusions. Journal Of Psychopharmacology 2007, 21: 238-252. PMID: 17591652, DOI: 10.1177/0269881107077716.Peer-Reviewed Original ResearchConceptsDelusion formationAssociative learning processesPrediction error signalsDevelopment of delusionsFormation of delusionsPre-psychotic periodAttentional disruptionAttentional disturbancesNeuropsychiatric modelsNeurobiological systemsPrediction errorExperience resultsLearning processIrrelevant detailsDelusionsError signalDrug ketaminePsychosisNumerous associationsPsychotic statesPerceptExpectationsPharmacological modelStimuliSymptom evolution
2005
Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens
Dalley J, Lääne K, Theobald D, Armstrong H, Corlett P, Chudasama Y, Robbins T. Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 6189-6194. PMID: 15833811, PMCID: PMC556132, DOI: 10.1073/pnas.0502080102.Peer-Reviewed Original ResearchConceptsAppetitive Pavlovian learningEarly memory consolidationNMDA receptor antagonistNucleus accumbensPavlovian memoryPavlovian learningAppetitive learningAssociative processesMemory consolidationApproach behaviorInstrumental learningPavlovian conditioningAppetitive memoryFood rewardReceptor antagonistConditioning sessionsNMDA receptorsSpatial learningInstrumental processesGlutamatergic influencesEarly consolidationD2 receptor antagonist sulpirideReceptor antagonist sulpirideIntra-NAc infusionsLearning