Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol
Kitay B, Murphy E, Macaluso M, Corlett P, Hershenberg R, Joormann J, Martinez-Kaigi V, Nikayin S, Rhee T, Sanacora G, Shelton R, Thase M, Wilkinson S. Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol. Psychiatry Research 2023, 330: 115585. PMID: 37935086, DOI: 10.1016/j.psychres.2023.115585.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMajor depressionSuicidal ideationRelapse preventionBehavioral therapyStudy protocolHigh riskClinical trial study protocolLong-term treatment approachKey secondary outcomesTrial study protocolHigh relapse rateHigh-risk populationSignificant suicidal ideationHospital dischargeSecondary outcomesPrimary outcomeRelapse rateFeasibility trialEsketamineTreatment approachesPatientsSuicide attemptsTherapySupplemental indicationsSelf-reported Gesture Interpretation and Performance Deficits in Individuals at Clinical High Risk for Psychosis
Karp E, Williams T, Ellman L, Strauss G, Walker E, Corlett P, Woods S, Powers A, Gold J, Schiffman J, Waltz J, Silverstein S, Mittal V. Self-reported Gesture Interpretation and Performance Deficits in Individuals at Clinical High Risk for Psychosis. Schizophrenia Bulletin 2023, 49: 746-755. PMID: 36939086, PMCID: PMC10154698, DOI: 10.1093/schbul/sbac197.Peer-Reviewed Original ResearchConceptsClinical high riskGesture deficitsInternalizing disordersCHR groupGesture interpretationLower verbal learningViable assessment toolVerbal learningNeurocognitive tasksGeneral intelligencePerformance deficitsNonverbal behaviorProcessing speedCHR participantsSimilar deficitsGreater deficitsHigh riskClinical InterviewFull psychotic disorderDeficitsSpecific subdomainsSRGPPsychotic disordersPsychosisGesturesComparing a Computerized Digit Symbol Test to a Pen-and-Paper Classic
Pratt D, Luther L, Kinney K, Osborne K, Corlett P, Powers A, Woods S, Gold J, Schiffman J, Ellman L, Strauss G, Walker E, Zinbarg R, Waltz J, Silverstein S, Mittal V. Comparing a Computerized Digit Symbol Test to a Pen-and-Paper Classic. Schizophrenia Bulletin Open 2023, 4: sgad027. PMID: 37868160, PMCID: PMC10590153, DOI: 10.1093/schizbullopen/sgad027.Peer-Reviewed Original ResearchClinical high riskCHR individualsFinger-tapping taskMotor ability measuresDigit symbol testCHR stateHealthy controlsHigh riskClinical InterviewPersistent subgroupSymbol testPersistent groupImpairmentPaper versionMotor abilitiesTask performance differencesComputerized versionSimilar degreeEffect sizeMeasures impairmentPsychosisCoding TestRemote assessmentSubgroupsDigit-symbol task