2024
Differing Pattern of Mismatch Negativity Responses in Clinical and Nonclinical Voice Hearers Challenge Predictive Coding Accounts of Psychosis
Erickson M, Bansal S, Li C, Waltz J, Corlett P, Gold J. Differing Pattern of Mismatch Negativity Responses in Clinical and Nonclinical Voice Hearers Challenge Predictive Coding Accounts of Psychosis. Biological Psychiatry Global Open Science 2024, 5: 100394. PMID: 39526022, PMCID: PMC11550737, DOI: 10.1016/j.bpsgos.2024.100394.Peer-Reviewed Original ResearchHealthy comparison subjectsReduced mismatch negativityPrediction error signalsPositive symptomsMismatch negativityDeviant typesPredictive coding accountPresence of hallucinationsMismatch negativity paradigmAuditory memory tracesComparison subjectsCoding accountMemory tracesPsychiatric illnessMMN responseVoice hearersRepetitive positioningError signalDuration conditionsHallucinationsHigher-levelDMMNDifferent patternsSymptomsPSZImagination, Agency, and Predictive Processing
Corlett P. Imagination, Agency, and Predictive Processing. 2024, 60-78. DOI: 10.1093/oso/9780198872221.003.0004.Peer-Reviewed Original ResearchPredictive processing theoryTheories of delusionsPredictive coding theorySensory inputDelusion formationSource monitoringProcess theoryDelusionsMediated learningHallucinationsConscious experienceImaginative processesReality perceptionPrediction processNeurocomputer architectureBeliefsPerceptionDysfunction
2023
Using dimensionality-reduction techniques to understand the organization of psychotic symptoms in persistent psychotic illness and first episode psychosis
Fleming L, Lemonde A, Benrimoh D, Gold J, Taylor J, Malla A, Joober R, Iyer S, Lepage M, Shah J, Corlett P. Using dimensionality-reduction techniques to understand the organization of psychotic symptoms in persistent psychotic illness and first episode psychosis. Scientific Reports 2023, 13: 4841. PMID: 36964175, PMCID: PMC10039017, DOI: 10.1038/s41598-023-31909-w.Peer-Reviewed Original ResearchConceptsHallucinations/delusionsFirst-episode psychosisFirst-episode psychosis participantsEarly intervention programsPathophysiological mechanismsUnderlying pathophysiologyEpisode psychosisPsychotic illnessPsychotic symptomsPsychotic disordersSchizoaffective disorderAuditory hallucinationsPositive symptomsHallucination severityNegative symptomsSymptomsDisorganization symptomsIntervention programsHallucinationsIllnessPsychosis participantsPsychosisDelusionsDisordersParticipants
2017
2.1 Transcranial Magnetic Stimulation for Voices That Are Distressing
Corlett P. 2.1 Transcranial Magnetic Stimulation for Voices That Are Distressing. Schizophrenia Bulletin 2017, 43: s1-s1. PMCID: PMC5475441, DOI: 10.1093/schbul/sbx021.002.Peer-Reviewed Original ResearchTranscranial magnetic stimulationFunctional magnetic resonance imagingWernicke's areaMagnetic stimulationDaily transcranial magnetic stimulationBilateral transcranial magnetic stimulationBrains of patientsDouble-cone coilMagnetic resonance imagingIntrinsic connectivity analysesAuditory verbal hallucinationsMechanisms of hallucinationsInsula cortexAuditory hallucinationsResonance imagingOrbitofrontal cortexNeural circuitryPatientsInsulaVerbal hallucinationsAberrant activityHallucinationsBrain activityEffective connectivityPrecise treatment