2008
Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity
Kerfoot SM, Szczepanik M, Tung JW, Askenase PW. Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity. The Journal Of Immunology 2008, 181: 1717-1727. PMID: 18641308, DOI: 10.4049/jimmunol.181.3.1717.Peer-Reviewed Original ResearchConceptsContact sensitivityB cellsCS initiationInflammatory responseT cell-mediated inflammationProinflammatory T cellsCell-mediated inflammationAdoptive transfer experimentsDelayed-type hypersensitivityAg-specific IgMReceptor gene mutationsSensitized miceVascular activationDeficient recipientsT cellsNovel subsetSomatic hypermutationNovel subpopulationGene mutationsIgMMiceActivation-Induced DeaminaseWT cellsCellsChain gene
1977
Cuta neous basophil responses in neonatal guinea pigs: active immunization, hapten specific transfer with small amounts of serum, and preferential elicitation with phytohemagglutinin skin testing.
Haynes J, Askenase P. Cuta neous basophil responses in neonatal guinea pigs: active immunization, hapten specific transfer with small amounts of serum, and preferential elicitation with phytohemagglutinin skin testing. The Journal Of Immunology 1977, 118: 1063-9. PMID: 845431, DOI: 10.4049/jimmunol.118.3.1063.Peer-Reviewed Original ResearchConceptsNeonatal guinea pigsIncomplete Freund's adjuvantMononuclear cellsCutaneous basophil hypersensitivityGuinea pigsBasophil responsePPD reactionSkin testFreund's adjuvantDelayed skin test responsesDelayed hypersensitivity skin responseHapten-specific mannerNonimmune guinea pigsDelayed-type reactionsSkin test responsesInfiltration of eosinophilsAdult guinea pigsCutaneous basophil responseIntravenous transferCutaneous basophil hypersensitivity reactionNeonatal responsesAdult donorsCutaneous reactionsNeonatesHapten-carrier conjugates