2021
Brain Structure and Function of Chronic Low Back Pain Patients on Long-Term Opioid Analgesic Treatment: A Preliminary Study
Murray K, Lin Y, Makary MM, Whang PG, Geha P. Brain Structure and Function of Chronic Low Back Pain Patients on Long-Term Opioid Analgesic Treatment: A Preliminary Study. Molecular Pain 2021, 17: 1744806921990938. PMID: 33567986, PMCID: PMC7883154, DOI: 10.1177/1744806921990938.Peer-Reviewed Original ResearchConceptsChronic low back painOpioid analgesicsCLBP patientsPain patientsChronic low back pain patientsLow back pain patientsBrain structuresOpioid analgesic treatmentBack pain patientsClasses of medicationsChronic pain patientsLow back painLong-term riskAltered brain structureSub-cortical areasOverall significant decreaseEvidence of misuseAnalgesic treatmentChronic treatmentBack painFunctional brain imagingLimbic areasUnmedicated patientsHealthy controlsNucleus accumbens
2016
Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. NonSurgical Management for Sacroiliac Joint Dysfunction
Polly D, Cher D, Wine K, Whang P, Frank C, Lockstadt H, Harvey C, Sembrano J. Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. NonSurgical Management for Sacroiliac Joint Dysfunction. Global Spine Journal 2016, 6: s-0036-1583136-s-0036-1583136. DOI: 10.1055/s-0036-1583136.Peer-Reviewed Original ResearchTriangular titanium implantsSI joint dysfunctionSI joint fusionSacroiliac joint dysfunctionSurgical groupJoint dysfunctionNonsurgical managementQuality of lifeJoint fusionSIJ fusionInvasive SI joint fusionInvasive Sacroiliac Joint FusionSacroiliac joint fusionLow back painRandomized Controlled TrialsImmediate revision surgerySuccess rateTitanium implantsODI improvementNeuropathic painSIJ painAdverse eventsNSM groupControlled TrialsNonsurgical treatmentTwo-Year Outcomes from a Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion vs. Non-Surgical Management for Sacroiliac Joint Dysfunction.
Polly DW, Swofford J, Whang PG, Frank CJ, Glaser JA, Limoni RP, Cher DJ, Wine KD, Sembrano JN. Two-Year Outcomes from a Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion vs. Non-Surgical Management for Sacroiliac Joint Dysfunction. The International Journal Of Spine Surgery 2016, 10: 28. PMID: 27652199, PMCID: PMC5027818, DOI: 10.14444/3028.Peer-Reviewed Original ResearchSubstantial clinical benefitNon-surgical treatmentSacroiliac joint dysfunctionTriangular titanium implantsClinical improvementMonth 24Clinical benefitSIJ painNSM groupSIJ dysfunctionJoint dysfunctionChronic low back painInvasive Sacroiliac Joint FusionChronic SIJ dysfunctionUnderwent revision surgeryNon-surgical managementTwo-Year OutcomesSacroiliac joint fusionLow back painProportion of subjectsQuality of lifeODI scoresSIJ fusionPain scoresSurgery group
2015
Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs Nonsurgical Management for Sacroiliac Joint Dysfunction: 12-Month Outcomes
Polly DW, Cher DJ, Wine KD, Whang PG, Frank CJ, Harvey CF, Lockstadt H, Glaser JA, Limoni RP, Sembrano JN. Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs Nonsurgical Management for Sacroiliac Joint Dysfunction: 12-Month Outcomes. Neurosurgery 2015, 77: 674-691. PMID: 26291338, PMCID: PMC4605280, DOI: 10.1227/neu.0000000000000988.Peer-Reviewed Original ResearchConceptsTriangular titanium implantsQuality of lifeSacroiliac joint dysfunctionSurgical groupNonsurgical managementSIJ dysfunctionSIJ fusionJoint dysfunctionOswestry Disability Index improvementSix-month success rateInvasive Sacroiliac Joint FusionChronic SIJ dysfunctionInvasive SIJ fusionNonsurgical management groupsOswestry Disability IndexSacroiliac joint fusionLow back painRandomized Controlled TrialsLevel 1 studiesSuccess rateTitanium implantsDegenerative sacroiliitisSIJ disruptionDisability IndexSIJ painSacroiliac Joint Fusion Using Triangular Titanium Implants vs. Non-Surgical Management: Six-Month Outcomes from a Prospective Randomized Controlled Trial
Whang P, Cher D, Polly D, Frank C, Lockstadt H, Glaser J, Limoni R, Sembrano J. Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. Non-Surgical Management: Six-Month Outcomes from a Prospective Randomized Controlled Trial. The International Journal Of Spine Surgery 2015, 9: 6. PMID: 25785242, PMCID: PMC4360612, DOI: 10.14444/2006.Peer-Reviewed Original ResearchSI joint dysfunctionSI joint fusionTriangular titanium implantsInvasive SI joint fusionQuality of lifeOswestry Disability IndexNon-surgical managementNon-surgical treatmentJoint dysfunctionJoint fusionDegenerative sacroiliitisJoint disruptionAdverse eventsJoint painSurgical groupSix monthsSix-month success rateProspective Randomized Controlled TrialJoint pain scoresSI joint painNon-surgical groupSacroiliac joint painShort Form-36Six-month outcomesLow back pain
2006
Animal models of spine fusion and low back pain
Poelstra K, Austin L, Zaslavsky J, Whang P, Patel A. Animal models of spine fusion and low back pain. Current Orthopaedic Practice 2006, 17: 214-221. DOI: 10.1097/01.bco.0000223529.57395.b8.Peer-Reviewed Original ResearchAnimal modelsCircumferential spinal fusionLow back painNew treatment strategiesReviews animal modelsBasic science advancesIntervertebral disc degenerationProgressive diseaseBack painTreatment strategiesSpinal fusionSpine fusionImproved careSurgical solutionPatient careDisc degenerationPainCarePivotal roleOsteoinductive agentsWide spectrumPatientsDegenerationDiseaseSurgeons