2023
Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease
Dhodapkar M, Halperin S, Saifi C, Whang P, Grauer J, Varthi A. Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease. The Spine Journal 2023, 24: 807-811. PMID: 38081460, DOI: 10.1016/j.spinee.2023.11.025.Peer-Reviewed Original ResearchPosterior lumbar interbody fusionSingle-level posterior lumbar interbody fusionSickle cell diseaseElixhauser Comorbidity IndexAdverse eventsPostoperative outcomesInterbody fusionOdds ratioCell diseaseDays adverse eventsMinor adverse eventsPostoperative adverse eventsPerioperative adverse eventsSevere adverse eventsCohort of patientsED visit ratesEmergency department visitsMultivariable logistic regressionNational administrative databaseRetrospective database studyLumbar interbody fusionSingle level posteriorComorbidity indexPLIF patientsAdult patientsEvolving Trends in the Use of Sacroiliac Fusion From 2015 to 2020
Halperin S, Dhodapkar M, Jiang W, Elaydi A, Jordan Y, Whang P, Grauer J. Evolving Trends in the Use of Sacroiliac Fusion From 2015 to 2020. Spine 2023, 49: 577-582. PMID: 37075329, DOI: 10.1097/brs.0000000000004684.Peer-Reviewed Original ResearchSI fusionOpen approachAdverse eventsSacroiliac fusionHigher Elixhauser comorbidity indexRetrospective cohort analysisElixhauser Comorbidity IndexLess adverse eventsEvolution of patientsComorbidity indexAdult patientsPatient characteristicsPrimary outcomeIndependent predictorsPearlDiver databaseMultivariable analysisPatient populationOpen procedureBACKGROUND DATACohort analysisSI jointDegenerative indicationsMIS approachMIS casesOlder age
2022
Comparison of postoperative outcomes in patients with and without osteoporosis undergoing single-level anterior cervical discectomy and fusion
Kammien AJ, Galivanche AR, Joo PY, Elaydi A, Whang P, Saifi C, Grauer JN, Varthi A. Comparison of postoperative outcomes in patients with and without osteoporosis undergoing single-level anterior cervical discectomy and fusion. North American Spine Society Journal (NASSJ) 2022, 12: 100174. PMID: 36299450, PMCID: PMC9589019, DOI: 10.1016/j.xnsj.2022.100174.Peer-Reviewed Original ResearchSingle-level anterior cervical discectomyAnterior cervical discectomyAdverse eventsCervical discectomySingle-level ACDF proceduresSurgical planningComorbidity-matched patientsPerioperative adverse eventsSingle-level ACDFLog-rank analysisLong-term outcomesNational administrative databaseSetting of osteoporosisACDF proceduresConcomitant proceduresPatient characteristicsPostoperative outcomesGraft subsidenceOsteoporosis groupBony unionPatient counselingPatient counsellingAdministrative databasesReoperationExclusion criteriaA comparison of in-hospital outcomes after elective anterior cervical discectomy and fusion in cases with and without Parkinson's Disease
Galivanche AR, Schneble CA, David WB, Mercier MR, Kammien AJ, Ottesen TD, Saifi C, Whang PG, Grauer JN, Varthi AG. A comparison of in-hospital outcomes after elective anterior cervical discectomy and fusion in cases with and without Parkinson's Disease. North American Spine Society Journal (NASSJ) 2022, 12: 100164. PMID: 36304443, PMCID: PMC9594612, DOI: 10.1016/j.xnsj.2022.100164.Peer-Reviewed Original ResearchMinor adverse eventsSerious adverse eventsAnterior cervical discectomyAdverse eventsParkinson's diseaseElective ACDFComorbidity burdenCervical discectomyMedical complicationsPD casesElective anterior cervical discectomyNational Inpatient Sample databaseGreater riskAssociation of PDCervical degenerative pathologyPostoperative medical complicationsLogistic regression modelsHospital complicationsHospital outcomesComplication rateSurgical complicationsUnmatched populationACDF casesSurgical interventionComorbidity variablesAcute postoperative neurological complications after spine surgery#
Toombs C, Whang P. Acute postoperative neurological complications after spine surgery#. Seminars In Spine Surgery 2022, 34: 100927. DOI: 10.1016/j.semss.2022.100927.Peer-Reviewed Original Research
2021
Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Galivanche AR, Toombs C, Adrados M, David WB, Malpani R, Saifi C, Whang PG, Grauer JN, Varthi AG. Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly. Neurospine 2021, 18: 226-233. PMID: 33819949, PMCID: PMC8021820, DOI: 10.14245/ns.2040620.310.Peer-Reviewed Original ResearchVertebral compression fracturesAdverse eventsCompression fracturesCement augmentationAge categoriesNational Surgical Quality Improvement Program databaseInpatient/outpatient statusQuality Improvement Program databaseProcedural variablesMinor adverse eventsImprovement Program databaseSerious adverse eventsMultivariate logistic regressionYear old cohortPeriprocedure complicationsOlder patientsComorbidity statusOutpatient statusRetrospective reviewAdverse outcomesGeriatric populationProcedure typeProgram databaseProvider specialtyChi-square analysis
2018
Practice Patterns and Treatment Challenges in Acute Postoperative Pain Management: A Survey of Practicing Physicians
Gan TJ, Epstein RS, Leone-Perkins ML, Salimi T, Iqbal SU, Whang PG. Practice Patterns and Treatment Challenges in Acute Postoperative Pain Management: A Survey of Practicing Physicians. Pain And Therapy 2018, 7: 205-216. PMID: 30367388, PMCID: PMC6251830, DOI: 10.1007/s40122-018-0106-9.Peer-Reviewed Original ResearchAcute postoperative painMedication-related adverse eventsPostoperative pain managementPostoperative painAdverse eventsPain managementAnalgesic medicationPrescribing decisionsUnmet needPatient-related risk factorsAcute postoperative pain managementEffective analgesic medicationsAcute pain managementPoor overall outcomeHigh-risk patientsSevere postoperative painOnset of analgesiaPatient-related factorsAnti-inflammatory drugsCOX-2 inhibitorsKey unmet needPractice-related factorsMethodsBetween AprilTop unmetAnalgesic therapy
2016
Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. NonSurgical Management for Sacroiliac Joint Dysfunction
Polly D, Cher D, Wine K, Whang P, Frank C, Lockstadt H, Harvey C, Sembrano J. Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. NonSurgical Management for Sacroiliac Joint Dysfunction. Global Spine Journal 2016, 6: s-0036-1583136-s-0036-1583136. DOI: 10.1055/s-0036-1583136.Peer-Reviewed Original ResearchTriangular titanium implantsSI joint dysfunctionSI joint fusionSacroiliac joint dysfunctionSurgical groupJoint dysfunctionNonsurgical managementQuality of lifeJoint fusionSIJ fusionInvasive SI joint fusionInvasive Sacroiliac Joint FusionSacroiliac joint fusionLow back painRandomized Controlled TrialsImmediate revision surgerySuccess rateTitanium implantsODI improvementNeuropathic painSIJ painAdverse eventsNSM groupControlled TrialsNonsurgical treatment
2015
Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. Non-Surgical Management: Six-Month Outcomes from a Prospective Randomized Controlled Trial
Whang P, Cher D, Polly D, Frank C, Lockstadt H, Glaser J, Limoni R, Sembrano J. Sacroiliac Joint Fusion Using Triangular Titanium Implants vs. Non-Surgical Management: Six-Month Outcomes from a Prospective Randomized Controlled Trial. The International Journal Of Spine Surgery 2015, 9: 6. PMID: 25785242, PMCID: PMC4360612, DOI: 10.14444/2006.Peer-Reviewed Original ResearchSI joint dysfunctionSI joint fusionTriangular titanium implantsInvasive SI joint fusionQuality of lifeOswestry Disability IndexNon-surgical managementNon-surgical treatmentJoint dysfunctionJoint fusionDegenerative sacroiliitisJoint disruptionAdverse eventsJoint painSurgical groupSix monthsSix-month success rateProspective Randomized Controlled TrialJoint pain scoresSI joint painNon-surgical groupSacroiliac joint painShort Form-36Six-month outcomesLow back pain
2013
Comparison of Axial and Anterior Interbody Fusions of the L5–S1 Segment
Whang PG, Sasso RC, Patel VV, Ali RM, Fischgrund JS. Comparison of Axial and Anterior Interbody Fusions of the L5–S1 Segment. Clinical Spine Surgery A Spine Publication 2013, 26: 437-443. PMID: 24196923, DOI: 10.1097/bsd.0b013e318292aad7.Peer-Reviewed Original ResearchConceptsAnterior lumbar interbody fusionAdverse eventsInterbody fusionPosterior fixationDevice-related adverse eventsL5-S1 interbody fusionL5-S1 disc spaceAnterior interbody fusionAnterior retroperitoneal approachSerious intraoperative complicationsAnterior column supportDifferent surgical approachesLumbar interbody fusionRadiographic fusion rateL5-S1 segmentSupplemental posterior fixationAxiaLIF techniqueHospital chartsIntraoperative complicationsMulticenter reviewRadiographic successRetroperitoneal approachArthrodesis ratesPresacral spaceProcedural dataMitigating Adverse Event Reporting Bias in Spine Surgery
Auerbach JD, McGowan KB, Halevi M, Gerling MC, Sharan AD, Whang PG, Maislin G. Mitigating Adverse Event Reporting Bias in Spine Surgery. Journal Of Bone And Joint Surgery 2013, 95: 1450-1456. PMID: 23965694, DOI: 10.2106/jbjs.l.00251.Peer-Reviewed Original ResearchConceptsIndependent clinical events committeeClinical events committeeAdverse eventsClinical trialsLevels of severityInvestigational device exemption studyFuture clinical trialsAdverse event dataLumbar spinal fusionAdverse event reportingAdverse event reportsSpinal stenosisEvents committeeSafety profileSurgery StudyFusion groupInvestigator biasSpine surgerySpinal fusionSpine surgeonsSurgeryInvestigational deviceStudy sponsorEvent reportingFinancial interests
2011
A novel technique for preparing an allograft fibula for use as a transsacral graft as treatment for high-grade spondylolisthesis.
Milewski MD, Whang PG, Grauer JN. A novel technique for preparing an allograft fibula for use as a transsacral graft as treatment for high-grade spondylolisthesis. The American Journal Of Orthopedics 2011, 40: 130-3, 138. PMID: 21738906.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligamentInstrumented posterolateral fusionFibular allograftPosterolateral fusionHigh-grade spondylolisthesisAllograft fibulaIndex surgerySixth patientAdverse eventsIntraoperative complicationsProminent hardwareCruciate ligamentAllograftsPatientsS1 segmentPosterior implantationDeformityReamerL5ComplicationsSpondylolisthesisSurgeryGraftIleumYears
2007
The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Vaccaro AR, Whang PG, Patel T, Phillips FM, Anderson DG, Albert TJ, Hilibrand AS, Brower RS, Kurd MF, Appannagari A, Patel M, Fischgrund JS. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. The Spine Journal 2007, 8: 457-465. PMID: 17588821, DOI: 10.1016/j.spinee.2007.03.012.Peer-Reviewed Original ResearchConceptsOP-1 PuttyUninstrumented fusionIliac crest autograftDegenerative spondylolisthesisOverall success rateAutograft patientsX-ray filmsAdverse eventsDecompressive laminectomyCrest autograftAutogenous boneShort Form Health Survey scoresForm Health Survey scoresBone graft substituteAutogenous iliac crest bone graftIliac crest bone graftPatient-reported outcome measuresPilot studyIntermediate-term efficacyOswestry Disability IndexPreoperative Oswestry scoreHealth Survey scoresPrimary efficacy endpointSF-36 scoresSymptomatic spinal stenosis