The contribution of metal ions to the structural stability of the large ribosomal subunit
Klein DJ, Moore PB, Steitz TA. The contribution of metal ions to the structural stability of the large ribosomal subunit. RNA 2004, 10: 1366-1379. PMID: 15317974, PMCID: PMC1370624, DOI: 10.1261/rna.7390804.Peer-Reviewed Original ResearchConceptsLarge ribosomal subunitRibosomal subunitMonovalent cation binding siteNucleotide basesSpecific RNA structuresPeptidyl transferase centerLarge RNA moleculesPhylogenetic kingdomsRibosomal proteinsAppearance of proteinsRRNA structureHaloarcula marismortuiMajor groove sideEvolutionary periodRNA moleculesRNA structureCation binding siteStructural domainsTertiary structureProtein groupsMonovalent cationsBinding sitesRRNAGroove sideSubunitsThe structure of a ribosomal protein S8/spc operon mRNA complex
Merianos HJ, Wang J, Moore PB. The structure of a ribosomal protein S8/spc operon mRNA complex. RNA 2004, 10: 954-964. PMID: 15146079, PMCID: PMC1370587, DOI: 10.1261/rna.7030704.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceBinding SitesCrystallography, X-RayEscherichia coliEscherichia coli ProteinsGenes, BacterialLigandsMacromolecular SubstancesModels, MolecularNucleic Acid ConformationOperonProtein BiosynthesisRibosomal ProteinsRNA, BacterialRNA, MessengerSpecies SpecificityStatic ElectricityConceptsSpc operon mRNAOperon mRNARibosomal protein cistronsSmall ribosomal subunitRibosomal initiation complexResolution crystal structureProtein synthesis resultsSpc operonAutogenous regulationTranslational repressionInitiation complexOwn mRNARibosomal subunitS8 bindingSequence differencesCistronInternal sequencesMRNAGenesConformational similarityBindingComplexesRetroregulationRRNAsOperon