2018
Superior real‐time polymerase chain reaction detection of Babesia microti parasites in whole blood utilizing high‐copy BMN antigens as amplification targets
Grabias B, Clement J, Krause PJ, Lepore T, Kumar S. Superior real‐time polymerase chain reaction detection of Babesia microti parasites in whole blood utilizing high‐copy BMN antigens as amplification targets. Transfusion 2018, 58: 1924-1932. PMID: 29664114, DOI: 10.1111/trf.14642.Peer-Reviewed Original ResearchConceptsParasites/mLBlood donorsBlood samplesSeroreactive antigensBabesia microti parasitesWhole bloodTransfusion-transmitted infectionsParasite nucleic acidsReal-time polymerase chain reactionWhole blood samplesPolymerase chain reaction detectionPolymerase chain reactionSensitive molecular assaysBlood productsClinical characterizationRT-PCR detectionReal-time polymerase chain reaction detectionLaboratory diagnosisBabesia microtiStudy designInfected ticksDilution panelsAntigenZoonotic diseaseBlood
2014
Blood transfusion transmission of the tick‐borne relapsing fever spirochete Borrelia miyamotoi in mice
Krause PJ, Hendrickson JE, Steeves TK, Fish D. Blood transfusion transmission of the tick‐borne relapsing fever spirochete Borrelia miyamotoi in mice. Transfusion 2014, 55: 593-597. PMID: 25251880, DOI: 10.1111/trf.12879.Peer-Reviewed Original ResearchConceptsTransfusion transmissionRed blood cellsBorrelia miyamotoiBlood transfusion transmissionMurine transfusion modelFever spirochete Borrelia miyamotoiSpirochete clearanceRecipient bloodC57BL/6 miceMouse recipientsTransfusion modelMouse modelTransfusionMurine bloodHuman infectionsWet mountLyme diseaseStudy designBlood cellsMiceMiyamotoiSpirochetemiaFever spirochetesBloodBodied ticks
2012
Preventing transfusion‐transmitted babesiosis: preliminary experience of the first laboratory‐based blood donor screening program
Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause PJ, Group T. Preventing transfusion‐transmitted babesiosis: preliminary experience of the first laboratory‐based blood donor screening program. Transfusion 2012, 52: 1523-1529. PMID: 22452654, DOI: 10.1111/j.1537-2995.2012.03612.x.Peer-Reviewed Original ResearchConceptsTransfusion-transmitted babesiosisCases of TTBPolymerase chain reactionBlood donorsThalassemia patientsCommon transfusion-transmitted infectionSickle cellsIndeterminate PCR resultsPositive IFA resultsTransfusion-transmitted infectionsInvestigational new drug applicationReal-time polymerase chain reactionUnscreened bloodDonor screeningPatientsIFA resultsDrug AdministrationNew drug applicationsPreliminary experienceIndirect immunofluorescenceBabesia microtiStudy designDrug applicationChain reactionPCR results