2021
Preventing Transfusion-Transmitted Babesiosis
Bloch EM, Krause PJ, Tonnetti L. Preventing Transfusion-Transmitted Babesiosis. Pathogens 2021, 10: 1176. PMID: 34578209, PMCID: PMC8468711, DOI: 10.3390/pathogens10091176.Peer-Reviewed Original ResearchTransfusion-transmitted babesiosisBlood donor testingHealthy blood donorsIntra-erythrocytic parasitesDonor surveillanceTransfusion transmissibleDonor testingHigh morbidityTransfusion recipientsSevere babesiosisBlood donorsBlood supplyBlood safetyHigh riskGlobal epidemiologyHuman babesiosisCausative agentMolecular assaysUnited StatesBabesiosisInfectionRiskMajor riskImmunopathogenesisMorbidity
2018
BmGPAC, an Antigen Capture Assay for Detection of Active Babesia microti Infection
Thekkiniath J, Mootien S, Lawres L, Perrin BA, Gewirtz M, Krause PJ, Williams S, Doggett J, Ledizet M, Mamoun C. BmGPAC, an Antigen Capture Assay for Detection of Active Babesia microti Infection. Journal Of Clinical Microbiology 2018, 56: 10.1128/jcm.00067-18. PMID: 30093394, PMCID: PMC6156295, DOI: 10.1128/jcm.00067-18.Peer-Reviewed Original ResearchConceptsHuman babesiosisBabesia microti infectionCapture enzyme-linked immunosorbent assayAntigen capture enzyme-linked immunosorbent assayAntigen capture assayEnzyme-linked immunosorbent assayZoonotic infectious diseaseAcute infectionBlood transfusionAsymptomatic infectionMicroti infectionReal-time PCRBlood supplyAnimal reservoir hostsDonor bloodEpidemiological surveyHuman patientsImmune systemSerological assaysImmunodominant antigensInfectionInfectious diseasesIntraerythrocytic protozoan parasitePatientsImmunosorbent assayHuman Babesiosis Caused by a Babesia crassa–Like Pathogen: A Case Series
Jia N, Zheng YC, Jiang JF, Jiang RR, Jiang BG, Wei R, Liu HB, Huo QB, Sun Y, Chu YL, Fan H, Chang QC, Yao NN, Zhang WH, Wang H, Guo DH, Fu X, Wang YW, Krause PJ, Song JL, Cao WC. Human Babesiosis Caused by a Babesia crassa–Like Pathogen: A Case Series. Clinical Infectious Diseases 2018, 67: 1110-1119. PMID: 29538646, DOI: 10.1093/cid/ciy212.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionAsymptomatic infectionTick biteHuman babesiosisInfection 9 monthsRecent tick biteViral-like illnessCommon clinical manifestationsHaemaphysalis concinna ticksCase seriesInitial diagnosisClinical manifestationsOvarian tumorsModerate symptomsUS CentersBlood supplySevere diseaseHealthy residentsHealth problemsDisease controlInfectionChain reactionGenetic sequencingPatientsFurther investigation