1999
Different mutator phenotypes in Mlh1- versus Pms2-deficient mice
Yao X, Buermeyer A, Narayanan L, Tran D, Baker S, Prolla T, Glazer P, Liskay R, Arnheim N. Different mutator phenotypes in Mlh1- versus Pms2-deficient mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 6850-6855. PMID: 10359802, PMCID: PMC22005, DOI: 10.1073/pnas.96.12.6850.Peer-Reviewed Original ResearchConceptsMismatch repairMutator phenotypeMutation rateDifferent chromosomal locationsSingle-molecule PCRDinucleotide repeat lociMutation frequencyDNA mismatch repairMononucleotide repeat tractsChromosomal locationCellular processesDNA repair capacityHigh mutation frequencyDifferent mutator phenotypesMultiple genetic alterationsKnockout strainRepeat tractMlh1pMLH1 MMR geneRepeat lociGenetic alterationsDifferent tumor spectrumRepair capacityTumor developmentMMR genes
1989
UV-induced DNA-binding proteins in human cells.
Glazer P, Greggio N, Metherall J, Summers W. UV-induced DNA-binding proteins in human cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 1163-1167. PMID: 2919165, PMCID: PMC286646, DOI: 10.1073/pnas.86.4.1163.Peer-Reviewed Original ResearchMeSH KeywordsCycloheximideDactinomycinDNA ProbesDNA-Binding ProteinsHeLa CellsHumansMolecular WeightNuclear ProteinsUltraviolet RaysConceptsDose-dependent manner