2001
Triplex-induced Recombination in Human Cell-free Extracts DEPENDENCE ON XPA AND HsRad51*
Datta H, Chan P, Vasquez K, Gupta R, Glazer P. Triplex-induced Recombination in Human Cell-free Extracts DEPENDENCE ON XPA AND HsRad51*. Journal Of Biological Chemistry 2001, 276: 18018-18023. PMID: 11278954, DOI: 10.1074/jbc.m011646200.Peer-Reviewed Original Research
2000
High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells
Luo Z, Macris M, Faruqi A, Glazer P. High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 9003-9008. PMID: 10900269, PMCID: PMC16811, DOI: 10.1073/pnas.160004997.Peer-Reviewed Original ResearchConceptsTriple helix-forming oligonucleotidesLtk- cell lineTK geneChromosomal lociIntrachromosomal gene conversionMouse Ltk- cell lineSingle chromosomal locusFunctional tk geneGene conversion eventsSite-specific recombinationSequence-specific mannerCell linesSimplex virus thymidine kinase geneVirus thymidine kinase geneHerpes simplex virus thymidine kinase geneThymidine kinase geneGene conversionIdentical base compositionMammalian cellsDownstream genesConversion eventsChromosomal sitesBase compositionKinase geneMutant copies