2000
Gamma-Interferon-inducibleLysosomal Thiol Reductase (GILT) MATURATION, ACTIVITY, AND MECHANISM OF ACTION*
Phan U, Arunachalam B, Cresswell P. Gamma-Interferon-inducibleLysosomal Thiol Reductase (GILT) MATURATION, ACTIVITY, AND MECHANISM OF ACTION*. Journal Of Biological Chemistry 2000, 275: 25907-25914. PMID: 10852914, DOI: 10.1074/jbc.m003459200.Peer-Reviewed Original Research
1998
Intracellular formation and cell surface expression of a complex of an intact lysosomal protein and MHC class II molecules.
Arunachalam B, Pan M, Cresswell P. Intracellular formation and cell surface expression of a complex of an intact lysosomal protein and MHC class II molecules. The Journal Of Immunology 1998, 160: 5797-806. PMID: 9637490, DOI: 10.4049/jimmunol.160.12.5797.Peer-Reviewed Original ResearchAllelesAnimalsCell Transformation, ViralElectrophoresis, Polyacrylamide GelFlow CytometryFluorescent Antibody Technique, IndirectHerpesvirus 4, HumanHistocompatibility Antigens Class IIHLA-D AntigensHLA-DR AntigensLysosomesMiceOxidoreductasesOxidoreductases Acting on Sulfur Group DonorsProteinsRabbitsSodium Dodecyl SulfateSurface Properties
1994
MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding
Ortmann B, Androlewicz M, Cresswell P. MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding. Nature 1994, 368: 864-867. PMID: 8159247, DOI: 10.1038/368864a0.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsATP Binding Cassette Transporter, Subfamily B, Member 2ATP Binding Cassette Transporter, Subfamily B, Member 3ATP-Binding Cassette TransportersBeta 2-MicroglobulinBiological TransportB-LymphocytesCalcium-Binding ProteinsCalnexinCarrier ProteinsCell LineDigitoninEndoplasmic ReticulumHistocompatibility Antigens Class IHLA-A3 AntigenHumansMiceMolecular Sequence DataProtein BindingRabbitsSolubility
1987
Immune recognition of human major histocompatibility antigens: localization by a comprehensive synthetic strategy of the continuous antigenic sites in the first domain of HLA‐DR2 β chain
Ulrich R, Atassi H, Lutz P, Cresswell P, Atassi M. Immune recognition of human major histocompatibility antigens: localization by a comprehensive synthetic strategy of the continuous antigenic sites in the first domain of HLA‐DR2 β chain. European Journal Of Immunology 1987, 17: 497-502. PMID: 2436923, DOI: 10.1002/eji.1830170410.Peer-Reviewed Original ResearchConceptsAntibody-binding activityHuman major histocompatibility antigensBeta chainMajor histocompatibility antigensAntigenic sitesHistocompatibility antigensImmune recognitionChain antiserumIsolated beta chainsMost antiseraAntiserumPeptide 81Continuous antigenic sitesΒ-chainPeptidesFirst domainHLAImmunodominanceAntigenComprehensive synthetic strategy
1982
Expression of cell surface lectins on activated human lymphoid cells
Apgar J, Cresswell P. Expression of cell surface lectins on activated human lymphoid cells. European Journal Of Immunology 1982, 12: 570-576. PMID: 6214410, DOI: 10.1002/eji.1830120708.Peer-Reviewed Original Research
1981
A human leukocyte antigen identified by a monoclonal antibody
Berger A, Davis J, Cresswell P. A human leukocyte antigen identified by a monoclonal antibody. Human Immunology 1981, 3: 231-245. PMID: 6975769, DOI: 10.1016/0198-8859(81)90020-3.Peer-Reviewed Original ResearchConceptsLeukocyte antigenT cell linesB cell linesB lymphocytesCell linesMonoclonal antibodiesHuman leukocyte antigenPeripheral blood cellsBone marrow cellsAllogeneic cellsT cellsB cellsErythroid seriesMore antigensAntigenHuman leukocytesMarrow cellsBlood cellsNegative populationAntibodiesLymphocytesApproximate molecular weightCellsElectrophoretic mobilityMonocytes
1980
HLA-A2 as a target for cell-mediated lympholysis: Evidence from immunoselected HLA-A2 negative mutant cell lines
Andreotti P, Apgar J, Cresswell P. HLA-A2 as a target for cell-mediated lympholysis: Evidence from immunoselected HLA-A2 negative mutant cell lines. Human Immunology 1980, 1: 77-86. PMID: 7263311, DOI: 10.1016/0198-8859(80)90011-7.Peer-Reviewed Original ResearchConceptsCytotoxic T lymphocytesCell-mediated lympholysisHLA-A2T lymphocytesMixed lymphocyte responseHLA-A2 mutantsCell linesLymphocyte responsesHLA typingImmune precipitation analysisLymphocytesTarget cellsMolecular targetsSensitized cellsMutant cell linesComparable susceptibilityLympholysisHLAStaphylococcus aureus proteinPutative targetsAureus proteinNegative selectionCellsTargetSusceptibility
1978
Rabbit antiserum to human B-cell alloantigens II. Mechanism of inhibition of stimulation in the mixed lymphocyte response
Geier S, Cresswell P. Rabbit antiserum to human B-cell alloantigens II. Mechanism of inhibition of stimulation in the mixed lymphocyte response. Cellular Immunology 1978, 35: 392-402. PMID: 145900, DOI: 10.1016/0008-8749(78)90158-2.Peer-Reviewed Original ResearchConceptsAntibody-dependent cell-mediated cytotoxicityMixed lymphocyte responseAnti-B cell serumLymphocyte responsesDependent cell-mediated cytotoxicityInhibition of monocyteHuman B cell alloantigensADCC effector cellsCell-mediated cytotoxicityImmunoglobulin-positive cellsB-cell alloantigensRabbit antiserumEffector cellsMLR suppressionImmune eliminationStimulator cellsPositive cellsLevel of inhibitionMarked reductionCell populationsChicken antiseraAntiserumSimilar specificityMechanism of inhibitionFc region
1977
Robbit antisera to human B cell alloantigens: Effects on the mixed lymphocyte response
Geier S, Cresswell P. Robbit antisera to human B cell alloantigens: Effects on the mixed lymphocyte response. Cellular Immunology 1977, 28: 341-354. PMID: 139207, DOI: 10.1016/0008-8749(77)90117-4.Peer-Reviewed Original ResearchConceptsMixed lymphocyte responseB-lymphoblastoid cell linesHuman B lymphoblastoid cell lineB-cell alloantigensLymphoblastoid cell linesT-lymphoblastoid cell lineLymphocyte responsesHuman peripheral blood mononuclear cellsPeripheral blood mononuclear cellsPeripheral blood B lymphocytesHuman B cell alloantigensBlood B lymphocytesBlood mononuclear cellsHuman B cellsMononuclear cellsT lymphocytesB cellsB lymphocytesContinuous stimulationLymphocytesFab preparationsAlloantigensCell lines
1976
HLA antigens: rabbit antisera reacting with all A series or all B series specificities
Cresswell P, Ayres J. HLA antigens: rabbit antisera reacting with all A series or all B series specificities. European Journal Of Immunology 1976, 6: 82-88. PMID: 786698, DOI: 10.1002/eji.1830060203.Peer-Reviewed Original ResearchConceptsCytotoxicity of HLAHLA alloantiseraHLA antigensA2 substanceHuman peripheral blood lymphocytesPeripheral blood lymphocytesComplement-mediated cytotoxicityType of serumHLA-B12HLA-A2Blood lymphocytesHLA-B7Beta 2microglobulinHLAFragments of rabbitHLA lociCultured cell linesAntigenic determinantsAllelic productsRabbitsCell linesImmune precipitationRabbit antiserumAntigenAntiserum
1974
Immunological Identity of the Small Subunit of HL-A Antigens and β2-Microglobulin and Its Turnover on the Cell Membrane
Cresswell P, Springer T, Strominger J, Turner M, Grey H, Kubo R. Immunological Identity of the Small Subunit of HL-A Antigens and β2-Microglobulin and Its Turnover on the Cell Membrane. Proceedings Of The National Academy Of Sciences Of The United States Of America 1974, 71: 2123-2127. PMID: 4134761, PMCID: PMC388399, DOI: 10.1073/pnas.71.5.2123.Peer-Reviewed Original Research
1971
THE CYTOTOXIC EFFECT ON HUMAN LYMPHOCYTES OF RABBIT ANTISERA TO HUMAN FC (IGG)
WELSH K, CRESSWELL P, GOUJET C, SANDERSON A. THE CYTOTOXIC EFFECT ON HUMAN LYMPHOCYTES OF RABBIT ANTISERA TO HUMAN FC (IGG). Transplantation 1971, 12: 468-471. PMID: 5165966, DOI: 10.1097/00007890-197112000-00009.Peer-Reviewed Original Research