2001
Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers
Sant'Angelo D, Cresswell P, Janeway C, Denzin L. Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 6824-6829. PMID: 11381132, PMCID: PMC34437, DOI: 10.1073/pnas.121179998.Peer-Reviewed Original ResearchConceptsAllelic exclusionTCR heterodimerTCR proteinsCell surface expressionTCR lociT cellsCell surfaceFurther recombinationProteinAlpha chainBeta chainHeterodimersSurface expressionTransgenic miceTCR transgenic miceCellsAdditional mechanismExpressionTCR clonalityAssembly processGenesSecond TCRLociRNATCR
1998
Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC
Herberg J, Sgouros J, Jones T, Copeman J, Humphray S, Sheer D, Cresswell P, Beck S, Trowsdale J. Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC. European Journal Of Immunology 1998, 28: 459-467. PMID: 9521053, DOI: 10.1002/(sici)1521-4141(199802)28:02<459::aid-immu459>3.0.co;2-z.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntiportersATP Binding Cassette Transporter, Subfamily B, Member 2ATP-Binding Cassette TransportersBase SequenceCentromereExonsGenes, MHC Class IHistocompatibility Antigens Class IHumansImmunoglobulinsIntronsMembrane Transport ProteinsMiceMolecular Sequence DataPhylogenyRatsConceptsTapasin geneMouse ESTsSyntenic positionsGenomic analysisSeparate exonsGene sequencesDistinct phylogenyEndoplasmic reticulumGenesK locusChromosome 17IgC domainFunctional significanceLociMHC class IClass IHLA-DP locusTAP2 genesEquivalent locationsTAP transporterTapasin moleculePhylogenyIntronsChromosomesESTs