1999
Large-scale analysis of the yeast genome by transposon tagging and gene disruption
Ross-Macdonald P, Coelho P, Roemer T, Agarwal S, Kumar A, Jansen R, Cheung K, Sheehan A, Symoniatis D, Umansky L, Heidtman M, Nelson F, Iwasaki H, Hager K, Gerstein M, Miller P, Roeder G, Snyder M. Large-scale analysis of the yeast genome by transposon tagging and gene disruption. Nature 1999, 402: 413-418. PMID: 10586881, DOI: 10.1038/46558.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsDNA Transposable ElementsEscherichia coliFungal ProteinsGene Expression ProfilingGenetic TechniquesGenome, FungalMolecular Sequence DataMutagenesisOligonucleotide Array Sequence AnalysisOpen Reading FramesPhenotypePolymerase Chain ReactionSaccharomyces cerevisiaeTransformation, GeneticConceptsGene functionDisruption phenotypesLarge-scale analysisNon-annotated open reading framesGenome-wide analysisOpen reading frameSingle genetic backgroundTransposon taggingYeast genomeYeast mutantsGenomic scaleYeast SaccharomycesDifferent growth conditionsProtein localizationGene disruptionReading frameGene expressionFunctional analysisVegetative growthGenetic backgroundGenesGenomeTransposonGrowth conditionsYeast
1996
PhenoDB: An Integrated Client/Server Database for Linkage and Population Genetics
Cheung K, Nadkarni P, Silverstein S, Kidd J, Pakstis A, Miller P, Kidd K. PhenoDB: An Integrated Client/Server Database for Linkage and Population Genetics. Journal Of Biomedical Informatics 1996, 29: 327-337. PMID: 8812078, DOI: 10.1006/cbmr.1996.0024.Peer-Reviewed Original ResearchMeSH KeywordsAllelesComputer Communication NetworksComputer GraphicsComputer SystemsData Interpretation, StatisticalDatabase Management SystemsGene FrequencyGenetic LinkageGenetic MarkersGenetics, PopulationHumansInformation Storage and RetrievalInformation SystemsPedigreePhenotypeUser-Computer InterfaceConceptsClient/server databaseClient/server architectureData management tasksData analysis tasksUse graphical interfaceServer architectureDatabase applicationsComplex adServer databaseInteractive validationAnalysis tasksGraphical interfaceFile formatManagement tasksLarge datasetsPhenoDBMultipoint linkageGeneric formatHardy-Weinberg ratiosData entryEfficient managementProject managementGenetic marker dataPopulation geneticsTask