2000
An integrated web interface for large-scale characterization of sequence data
Cheung K, Kumar A, Snyder M, Miller P. An integrated web interface for large-scale characterization of sequence data. Functional & Integrative Genomics 2000, 1: 70-75. PMID: 11793223, DOI: 10.1007/s101420000004.Peer-Reviewed Original ResearchMeSH KeywordsClinical Laboratory Information SystemsComputational BiologyDatabases, GeneticDatabases, ProteinDNA Transposable ElementsDNA, FungalGene Expression ProfilingGenomeGenome, FungalInternetMutagenesis, InsertionalOpen Reading FramesSaccharomyces cerevisiaeSequence Analysis, DNASequence Homology, Nucleic AcidSoftwareUser-Computer InterfaceConceptsWeb interfaceWeb front endGenomic data processingData filesLarge-scale genome projectsIndependent software programsSet of programsMultiple directoriesData directoryData processingRaw dataTransposon insertion eventsSoftware programFilesFront endDirectoryEfficient protocolLarge amountInterfaceLarge numberGeneral approachUsersSetDownloadNavigation
1992
Fast Computation of Genetic Likelihoods on Human Pedigree Data
Goradia T, Lange K, Miller P, Nadkarni P. Fast Computation of Genetic Likelihoods on Human Pedigree Data. Human Heredity 1992, 42: 42-62. PMID: 1555846, DOI: 10.1159/000154045.Peer-Reviewed Original ResearchConceptsHuman pedigree dataNetwork of workstationsLarge-scale computationsHardware techniquesParallel machinesComputational speedDifferent architecturesLinkage problemFast computationVectorized versionComputationFast calculationLarge numberParallelizationSupercomputersVectorizationComplete phenotypingWorkstationsArchitectureGenetic likelihoodMachineNetworkVersionNew methodSubstantial improvement