An electroosmotic flow-free two-direction migration strategy enables fast affinity capillary electrophoresis to study the weak interactions between basic peptides and RNA
Yuan Z, Xu P, Yu F, Zhang D, Zhao Q, Yu W, Wang H. An electroosmotic flow-free two-direction migration strategy enables fast affinity capillary electrophoresis to study the weak interactions between basic peptides and RNA. Analytical Methods 2020, 12: 5833-5838. PMID: 33227112, DOI: 10.1039/d0ay01515f.Peer-Reviewed Original ResearchConceptsAffinity capillary electrophoresisCapillary electrophoresisWeak interactionsAffinity capillary electrophoresis methodHistone peptidesStudy noncovalent interactionsPeptide-RNA interactionsBinding complexPeptide-RNA complexesNoncovalent interactionsU2 RNACE migrationNeutral capillaryMethylation stateFast dissociationFree probeMigration strategyElectroosmotic flowRNAElectrophoresisMigration distancePeptideCE approachComplexElectric field