2019
Guide Positioning Sequencing identifies aberrant DNA methylation patterns that alter cell identity and tumor-immune surveillance networks
Li J, Li Y, Li W, Luo H, Xi Y, Dong S, Gao M, Xu P, Zhang B, Liang Y, Zou Q, Hu X, Peng L, Zou D, Wang T, Yang H, Jiang C, Peng S, Wu F, Yu W. Guide Positioning Sequencing identifies aberrant DNA methylation patterns that alter cell identity and tumor-immune surveillance networks. Genome Research 2019, 29: 270-280. PMID: 30670627, PMCID: PMC6360814, DOI: 10.1101/gr.240606.118.Peer-Reviewed Original ResearchConceptsWhole-genome bisulfite sequencingAberrant DNA methylationDNA methylationCell identityPredictor of gene expressionGenome-wide DNA methylationWhole-genome DNA methylationAberrant DNA methylation patternsDNA methylation patternsExpression of genes associated with immunityGenes associated with immunityAltering cell identityGene bodiesGC-richGenomic variationRepetitive regionsBisulfite sequencingMethylation patternsMethylation differencesGene expressionModulate expressionImmune surveillance networkLiver cancer developmentSequenceCancer development
2018
An epigenetic perspective on tumorigenesis: Loss of cell identity, enhancer switching, and NamiRNA network
Liang Y, Xu P, Zou Q, Luo H, Yu W. An epigenetic perspective on tumorigenesis: Loss of cell identity, enhancer switching, and NamiRNA network. Seminars In Cancer Biology 2018, 57: 1-9. PMID: 30213688, DOI: 10.1016/j.semcancer.2018.09.001.Peer-Reviewed Original ResearchAn epigenetic perspective on tumorigenesis: Loss of cell identity, enhancer switching, and NamiRNA network
Liang Y, Xu P, Zou Q, Luo H, Yu W. An epigenetic perspective on tumorigenesis: Loss of cell identity, enhancer switching, and NamiRNA network. Seminars In Cancer Biology 2018, 83: 596-604. PMID: 30208341, DOI: 10.1016/j.semcancer.2018.09.004.Peer-Reviewed Original Research