2021
A phase 2 evaluation of pembrolizumab for recurrent Lynch‐like versus sporadic endometrial cancers with microsatellite instability
Bellone S, Roque DM, Siegel ER, Buza N, Hui P, Bonazzoli E, Guglielmi A, Zammataro L, Nagarkatti N, Zaidi S, Lee J, Silasi D, Huang GS, Andikyan V, Damast S, Clark M, Azodi M, Schwartz PE, Tymon‐Rosario J, Harold JA, Mauricio D, Zeybek B, Menderes G, Altwerger G, Ratner E, Alexandrov LB, Iwasaki A, Kong Y, Song E, Dong W, Elvin JA, Choi J, Santin AD. A phase 2 evaluation of pembrolizumab for recurrent Lynch‐like versus sporadic endometrial cancers with microsatellite instability. Cancer 2021, 128: 1206-1218. PMID: 34875107, PMCID: PMC9465822, DOI: 10.1002/cncr.34025.Peer-Reviewed Original ResearchConceptsObjective response rateImmune checkpoint inhibitorsProgression-free survivalEndometrial cancerWhole-exome sequencingSporadic endometrial cancerOverall survivalEnd pointPhase 2 pilot studyPrimary end pointSecondary end pointsTumor mutation burdenPhase 2 evaluationLarger confirmatory studiesAntigen processing/presentationProcessing/presentationCheckpoint inhibitorsSurgical resectionICI resistanceDMMR patientsPrognostic significanceDMMR tumorsMechanisms of resistanceLocal treatmentSporadic MSI
2020
Genital tuberculosis screening at an academic fertility center in the United States
Tal R, Lawal T, Granger E, Simoni M, Hui P, Buza N, Pal L. Genital tuberculosis screening at an academic fertility center in the United States. American Journal Of Obstetrics And Gynecology 2020, 223: 737.e1-737.e10. PMID: 32497612, DOI: 10.1016/j.ajog.2020.05.045.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, HabitualAcademic Medical CentersAdultEndometritisEndometriumFemaleFertility ClinicsGynatresiaHumansIncidenceInfertility, FemaleInterferon-gamma Release TestsLatent TuberculosisMass ScreeningMycobacterium tuberculosisPolymerase Chain ReactionProspective StudiesTuberculosis, Female GenitalUnited StatesYoung AdultConceptsFemale genital tuberculosisQuantiFERON-TB GoldGenital tuberculosisAcademic fertility centerLatent tuberculosisChest X-rayPositive test resultsFertility centerPolymerase chain reactionEndometrial biopsyMycobacterium tuberculosisChain reactionQuantiFERON-TB Gold resultsProspective cohort studyRecurrent pregnancy lossReproductive technology treatmentAcid-fast bacilliMultiple diagnostic modalitiesNegative test resultsGranulomatous endometritisNeonatal complicationsEndometrial samplingNeonatal morbidityCohort studyAsherman's syndrome
2011
Reflex BRAF Testing in Thyroid Fine-Needle Aspiration Biopsy with Equivocal and Positive Interpretation: A Prospective Study
Adeniran AJ, Theoharis C, Hui P, Prasad ML, Hammers L, Carling T, Udelsman R, Chhieng DC. Reflex BRAF Testing in Thyroid Fine-Needle Aspiration Biopsy with Equivocal and Positive Interpretation: A Prospective Study. Thyroid 2011, 21: 717-723. PMID: 21568726, DOI: 10.1089/thy.2011.0021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBiomarkers, TumorBiopsy, Fine-NeedleCarcinomaCarcinoma, PapillaryChildDNA Mutational AnalysisFemaleHumansMaleMiddle AgedPoint MutationPolymorphism, Single-Stranded ConformationalProspective StudiesProto-Oncogene Proteins B-rafThyroid Cancer, PapillaryThyroid GlandThyroid Neoplasms