2021
Molecular Diagnosis
Weisman P, Wei J, Hui P. Molecular Diagnosis. Practical Anatomic Pathology 2021, 417-431. DOI: 10.1007/978-3-030-68608-6_16.Peer-Reviewed Original ResearchGynecologic pathologyMolecular diagnostic techniquesGynecologic tumorsCell tumorsTherapeutic implicationsOvarian sex cord-stromal tumorsHigh-grade endometrial stromal sarcomaSertoli-Leydig cell tumorSex cord-stromal tumorsJuvenile granulosa cell tumorMolecular diagnostic findingsSpindle cell leiomyosarcomaEndometrial stromal sarcomaGranulosa cell tumorsGestational trophoblastic diseaseLow mitotic ratePeutz-Jeghers syndromeDiagnostic techniquesFibrosarcoma-like tumorsStromal sarcomaOvarian neoplasiaSporadic settingHistological featuresTrophoblastic diseaseDiagnostic findings
2018
FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors
Buza N, Wong S, Hui P. FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors. International Journal Of Gynecological Pathology 2018, 37: 305-315. PMID: 28700438, DOI: 10.1097/pgp.0000000000000426.Peer-Reviewed Original ResearchConceptsSex cord-stromal tumorsAdult granulosa cell tumorGranulosa cell tumorsOvarian sex cord-stromal tumorsCell tumorsReticulin patternFOXL2 mutationStaining patternSertoli-Leydig cell tumorFOXL2 mutation statusAbundant pale cytoplasmSingle institutional cohortThird of casesWild-type tumorsFOXL2 mutation analysisNegative tumorsPositive tumorsTumor sizeReticulin stainingType tumorsPale cytoplasmNuclear atypiaMutation statusPositive casesTumors