2001
Transmission bottlenecks and the evolution of fitness in rapidly evolving RNA viruses
Elena S, Sanjuán R, Borderı́a A, Turner P. Transmission bottlenecks and the evolution of fitness in rapidly evolving RNA viruses. Infection Genetics And Evolution 2001, 1: 41-48. PMID: 12798049, DOI: 10.1016/s1567-1348(01)00006-5.Peer-Reviewed Original ResearchConceptsVesicular stomatitis virusRNA virusesEvolution of fitnessBasic genetic principlesNatural populationsGenetic driftEvolutionary importanceFitness lossCellular hostsTransmission bottleneckDeleterious mutationsHost individualsGenetic principlesBottleneck sizeViral adaptationViral fitnessStomatitis virusRandom accumulationSimilar bottlenecksTissue cultureMutationsFitnessProfound effectVirusMode of transmission
2000
Cost of Host Radiation in an RNA Virus
Turner P, Elena S. Cost of Host Radiation in an RNA Virus. Genetics 2000, 156: 1465-1470. PMID: 11102349, PMCID: PMC1461356, DOI: 10.1093/genetics/156.4.1465.Peer-Reviewed Original ResearchConceptsHost radiationNovel hostVesicular stomatitis virusOriginal hostHost environmentSubstantial fitness gainsMammalian host cellsNovel habitatsMultiple habitatsEcological nichesExperimental populationsFitness gainsWeak selectionHost typeNew hostGenetic materialHost cellsRNA virusesMultiple host typesReduced competitivenessStomatitis virusHabitatsSlow replicationHostFitness