Antibiotic resistance correlates with transmission in plasmid evolution
Turner PE, Williams ES, Okeke C, Cooper VS, Duffy S, Wertz JE. Antibiotic resistance correlates with transmission in plasmid evolution. Evolution 2014, 68: 3368-3380. PMID: 25351426, DOI: 10.1111/evo.12537.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsConjugation, GeneticDNA Transposable ElementsDrug Resistance, BacterialEscherichia coliEvolution, MolecularGene Transfer, HorizontalPlasmidsTetracyclineVirulenceConceptsCarbon source utilizationPreliminary sequence analysisAntibiotic resistance correlatesFitness assaysQuantitative traitsSelection pressureBacterial hostsResistance levelsPhenotypic performancePlasmid-bearing cellsGenetic rearrangementsTransfer operonSequence analysisPlasmid evolutionPlasmid conjugationCommon competitorPhenotypic correlationsShufflon regionTetracycline resistance transposonAutonomous replicatorPlasmidHorizontal transmissionDivergencePlasmid resistancePlasmid lineages