2024
Microbe Profile: Bacteriophage ϕ6: a model for segmented RNA viruses and the evolutionary consequences of viral ‘sex’
Turner P, Chao L. Microbe Profile: Bacteriophage ϕ6: a model for segmented RNA viruses and the evolutionary consequences of viral ‘sex’. Microbiology 2024, 170: 001467. PMID: 39046321, PMCID: PMC11316545, DOI: 10.1099/mic.0.001467.Peer-Reviewed Original ResearchConceptsEukaryotic virusesHost-pathogen interactionsEvolution of sexDsRNA virusesEvolutionary consequencesSegment reassortmentBacterial virusesRNA virusesRate of adaptationMutation ratePhenotypic complexityMutation loadLipid envelopeBacteriophageReassortmentRNAMutationsVirusMolecular modelingDsRNAExperimental systemGeneticsTraitsHostReplication
2023
Cheating leads to the evolution of multipartite viruses
Leeks A, Young P, Turner P, Wild G, West S. Cheating leads to the evolution of multipartite viruses. PLOS Biology 2023, 21: e3002092. PMID: 37093882, PMCID: PMC10159356, DOI: 10.1371/journal.pbio.3002092.Peer-Reviewed Original Research
2000
The Two Faces of Mutation: Extinction and Adaptation in RNA Viruses
Elena S, Miralles R, Cuevas J, Turner P, Moya A. The Two Faces of Mutation: Extinction and Adaptation in RNA Viruses. IUBMB Life 2000, 49: 5-9. PMID: 10772334, DOI: 10.1080/713803585.Peer-Reviewed Original ResearchConceptsRNA virusesPopulation sizeGenetic variabilityDrastic fitness lossFace of mutationCellular DNA replicationHigh genetic variabilityEffects of mutationsLarge population sizesViral population sizeBottleneck eventsGenetic driftFitness lossDNA replicationFitness gainsSegment exchangeDifferent tissuesViral extinctionReplicative intermediatesInfected hostExtinctionMutationsPopulation standpointHostReplication