1995
Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase
Boulanger L, Lombroso P, Raghunathan A, During M, Wahle P, Naegele. Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase. Journal Of Neuroscience 1995, 15: 1532-1544. PMID: 7869116, PMCID: PMC6577844, DOI: 10.1523/jneurosci.15-02-01532.1995.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAxonsBlotting, WesternBrainCerebral CortexCorpus StriatumImmunohistochemistryIn Situ HybridizationMiceMice, Inbred BALB CNeuronsPeptide FragmentsProtein Tyrosine PhosphatasesProtein Tyrosine Phosphatases, Non-ReceptorRatsRNA, MessengerSynaptic TransmissionTissue DistributionConceptsSubstantia nigraAdult rat brainCombination of immunocytochemistrySitu hybridization studiesProjection neuronsBasal gangliaCaudate putamenPresynaptic axonsStriatal enriched protein tyrosine phosphataseRat brainBrain regionsImmunocytochemical stainingLesion experimentsWestern blotLesion studiesWestern blottingMonoclonal antibodiesMRNA expression patternsImmunoreactive formsImmunoreactive bandsProtein tyrosine phosphataseNigraSitu hybridizationHybridization studiesSTEP isoforms
1994
Genetic Mechanisms in Childhood Psychiatric Disorders
LOMBROSO P, PAULS D, LECKMAN J. Genetic Mechanisms in Childhood Psychiatric Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1994, 33: 921-938. PMID: 7525534, DOI: 10.1097/00004583-199409000-00001.Peer-Reviewed Original ResearchMeSH KeywordsAdoptionAttention Deficit Disorder with HyperactivityAutistic DisorderChildChild, PreschoolChromosome AberrationsChromosome DisordersDevelopmental DisabilitiesDiseases in TwinsEnvironmentFamilyGenetic LinkageHumansInfantInfant, NewbornKaryotypingMood DisordersRNA, MessengerTourette SyndromeConceptsMolecular basisGenetic researchChildhood psychiatric disordersGenetic mechanismsPsychiatric disordersGenetic factorsMolecular understandingComplex behavioral disordersChildhood disordersGenetic etiologyCertain childhood disordersCertain developmental disordersDevelopmental disordersPsychiatric illness
1991
Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum.
Lombroso P, Murdoch G, Lerner M. Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 7242-7246. PMID: 1714595, PMCID: PMC52270, DOI: 10.1073/pnas.88.16.7242.Peer-Reviewed Original ResearchConceptsDeduced amino acid sequenceAmino acid consensus sequenceAmino acid sequenceApparent molecular massRat striatal cDNA librarySingle geneVitro translationCDNA clonesStrong homologyCDNA libraryCytoplasmic membraneAcid sequenceRNA transcriptsN-terminusMolecular characterizationRNA analysisMolecular massAmino acidsProteinPhosphataseMRNASequenceHomologyGenesTerminus