2023
Pulmonary artery wave intensity analysis in a pig model of lung resection
KEAST T, GLASS A, MCCALL P, SHELLEY B, HEERDT P. Pulmonary artery wave intensity analysis in a pig model of lung resection. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 9-10. DOI: 10.1053/j.jvca.2023.08.023.Peer-Reviewed Original ResearchForward compression waveBackward compression waveWave intensity analysisControl subjectsLung resectionPulmonary arteryPig modelSystolic timeCardiovascular MRIInvasive haemodynamic dataPulmonary artery pressureRight ventricular functionProximal pulmonary arteriesMain pulmonary arteryPost-operative patientsRight ventricular contractionWave reflection indicesMann-Whitney testIncreased afterloadLabChart softwareArtery pressureHaemodynamic effectsRV functionUpper lobectomyVentricular function
2007
Nitrosative Stress and Myocardial Sarcoplasmic Endoreticular Calcium Adenosine Triphosphatase Subtype 2a Activity after Lung Resection in Swine
Heerdt PM, Lane P, Pan BY, Schaefer U, Crabtree M, Hong R, Singer AA, Levi R, Park BJ. Nitrosative Stress and Myocardial Sarcoplasmic Endoreticular Calcium Adenosine Triphosphatase Subtype 2a Activity after Lung Resection in Swine. Anesthesiology 2007, 107: 954-962. PMID: 18043064, DOI: 10.1097/01.anes.0000291446.70921.61.Peer-Reviewed Original ResearchConceptsNitrosative stressForce-frequency relationLung resectionSERCA2a activityAcute oxidative stressOxidative stressPhosphorylation stateSubcellular processesBiochemical basisProtein phospholambanDisease-associated oxidative stressRegulatory protein phospholambanPhospholamban phosphorylationReticular membranesProtein expressionImpaired calcium cyclingPhosphorylationWestern blottingExpressionPerioperative changesUpper lobectomyPhospholamban expressionSham groupAcute eventChronic illness