2010
The Safety of Opioid Analgesics in the Elderly: New Data Raise New Concerns: Comment on “The Comparative Safety of Opioids for Nonmalignant Pain in Older Adults”
Becker WC, O'Connor PG. The Safety of Opioid Analgesics in the Elderly: New Data Raise New Concerns: Comment on “The Comparative Safety of Opioids for Nonmalignant Pain in Older Adults”. JAMA Internal Medicine 2010, 170: 1986-1988. PMID: 21149755, DOI: 10.1001/archinternmed.2010.443.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCardiovascular DiseasesComorbidityContraindicationsCyclooxygenase 2 InhibitorsDrug UtilizationFemaleFractures, BoneGastrointestinal HemorrhageHumansMaleMedicareObservationPainPain MeasurementResearch DesignTherapeutic EquivalencyUnited States
2009
Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain
Chou R, Fanciullo GJ, Fine PG, Adler JA, Ballantyne JC, Davies P, Donovan MI, Fishbain DA, Foley KM, Fudin J, Gilson AM, Kelter A, Mauskop A, O'Connor PG, Passik SD, Pasternak GW, Portenoy RK, Rich BA, Roberts RG, Todd KH, Miaskowski C, Panel A. Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain. Journal Of Pain 2009, 10: 113-130.e22. PMID: 19187889, PMCID: PMC4043401, DOI: 10.1016/j.jpain.2008.10.008.Peer-Reviewed Original ResearchConceptsChronic opioid therapyChronic noncancer painOpioid therapyNoncancer painMultidisciplinary expert panelExpert panelSystematic reviewHigh-dose opioid therapyOpioid-related adverse effectsAdverse effectsOpioid management plansDiscontinuation of therapyAmerican Pain SocietyUse of opioidsUse of methadoneMonitoring of patientsOpioid rotationBreakthrough painOpioid prescribingDose escalationPain SocietyPatient selectionRisk stratificationClinical guidelinesOpioid abuse