TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection
Reilly EC, Emo K, Buckley PM, Reilly NS, Smith I, Chaves FA, Yang H, Oakes PW, Topham DJ. TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 12306-12314. PMID: 32439709, PMCID: PMC7275699, DOI: 10.1073/pnas.1915681117.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CDCD8-Positive T-LymphocytesCell AdhesionCell MovementHumansImmunologic MemoryInfluenza A Virus, H3N2 SubtypeInfluenza, HumanIntegrin alpha ChainsIntegrin alpha1Mice, Inbred C57BLConceptsCD8 T cellsFunction of CD103Influenza virus infectionT cellsVirus infectionPeripheral tissuesTissue-resident memory CD8 T cellsVirus-specific CD8 T cellsMemory CD8 T cellsRole of CD69Site of infectionCell surface phenotypeT cell motilityMemory subsetsWk postinfectionSurface phenotypeCD103Pulmonary systemCD49aInfectionCD69Host resistanceTissueCellsExpression patterns