2021
The impact of COVID-19 on cancer care and oncology clinical research: an experts’ perspective
Sessa C, Cortes J, Conte P, Cardoso F, Choueiri T, Dummer R, Lorusso P, Ottmann O, Ryll B, Mok T, Tempero M, Comis S, Oliva C, Peters S, Tabernero J. The impact of COVID-19 on cancer care and oncology clinical research: an experts’ perspective. ESMO Open 2021, 7: 100339. PMID: 34953404, PMCID: PMC8608656, DOI: 10.1016/j.esmoop.2021.100339.Peer-Reviewed Original ResearchConceptsInnovative clinical trialsClinical trialsOncology clinical trialsOncology clinical researchClinical researchCancer careClinical trial stakeholdersTrial stakeholdersNew treatmentsPatient accessCancer clinical trialsCOVID-19COVID-19 pandemicNew trial designsFaster patient accessWorldwide clinical trialsClinical trial objectivesOncology expertsOutcome dataTrial designTrial objectivesTrialsRecent dataCareInternational panel
2014
AN INTEGRATED FRAMEWORK FOR REPORTING CLINICALLY RELEVANT BIOMARKERS FROM PAIRED TUMOR/NORMAL GENOMIC AND TRANSCRIPTOMIC SEQUENCING DATA IN SUPPORT OF CLINICAL TRIALS IN PERSONALIZED MEDICINE
Altman R, Dunker A, Hunter L, Ritchie M, Murray T, Klein T, NASSER S, KURDOGLU A, IZATT T, ALDRICH J, RUSSELL M, CHRISTOFORIDES A, TEMBE W, KIEFER J, CORNEVEAUX J, BYRON S, FORMAN K, ZUCCARO C, KEATS J, LORUSSO P, CARPTEN J, TRENT J, CRAIG D. AN INTEGRATED FRAMEWORK FOR REPORTING CLINICALLY RELEVANT BIOMARKERS FROM PAIRED TUMOR/NORMAL GENOMIC AND TRANSCRIPTOMIC SEQUENCING DATA IN SUPPORT OF CLINICAL TRIALS IN PERSONALIZED MEDICINE. Biocomputing 2014, 56-67. PMID: 25592568, DOI: 10.1142/9789814644730_0007.Peer-Reviewed Original ResearchConceptsTranscriptomic sequencing dataHigh-throughput genomic dataRelational database systemsTerabytes of dataTumor/normal samplesSingle nucleotide changeDiversity of usersReal-time mannerIndividual genomesAnnotation databasesDatabase systemsFlexible computational frameworkChromosomal rearrangementsGenomic dataGene expressionSequencing dataData structureComputational architectureGene fusionsNucleotide changesMultiple trackersBase pairsSmall insertionsTime mannerClinical genomic testing
1999
Accrual to Breast Cancer Clinical Trials at a University-Affiliated Hospital in Metropolitan Detroit
Simon M, Brown D, Du W, LoRusso P, Kellogg C. Accrual to Breast Cancer Clinical Trials at a University-Affiliated Hospital in Metropolitan Detroit. American Journal Of Clinical Oncology 1999, 22: 42-46. PMID: 10025379, DOI: 10.1097/00000421-199902000-00011.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsClinical Trials as TopicFemaleHospitals, UniversityHospitals, UrbanHumansMichiganMiddle AgedPatient SelectionPractice Patterns, Physicians'ConceptsBreast cancer clinical trialsClinical trialsCancer clinical trialsBreast cancerLarge urban university hospitalFemale breast cancer patientsEarly-stage diseaseUrban university hospitalBreast cancer patientsAvailable studiesUniversity Affiliated HospitalStage diseasePatient barriersMedical oncologistsBreast servicesPatient enrollmentCancer patientsPatient raceUniversity HospitalPractice patternsMost womenTrialsWomenEnrollment processMetropolitan Detroit