The role of GDC-0449, a hedgehog (Hh) pathway inhibitor, on epithelial–mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells lines and its effect on erlotinib and cisplatin.
Maitah M, Ali S, LoRusso P, Sarkar F, Gadgeel S. The role of GDC-0449, a hedgehog (Hh) pathway inhibitor, on epithelial–mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells lines and its effect on erlotinib and cisplatin. Journal Of Clinical Oncology 2011, 29: 10537-10537. DOI: 10.1200/jco.2011.29.15_suppl.10537.Peer-Reviewed Original ResearchNon-small cell lung cancerEpithelial-mesenchymal transitionCell lung cancerHedgehog pathway inhibitorsLung cancerPathway inhibitorErlotinibCancerCisplatin