2009
Evolution of the neocortex: a perspective from developmental biology
Rakic P. Evolution of the neocortex: a perspective from developmental biology. Nature Reviews Neuroscience 2009, 10: 724-735. PMID: 19763105, PMCID: PMC2913577, DOI: 10.1038/nrn2719.Peer-Reviewed Original ResearchConceptsEvo-devo approachSpecies-specific adaptationsExtinct common ancestorsNew cell typesSpecies-specific differencesMutations of genesProliferative ventricular zoneMammalian evolutionDistinct migratory pathwaysCommon ancestorDevelopmental biologyCell divisionNew traitsNew cell subtypesNeural stem cellsProtomap hypothesisMouse embryosNew cytoarchitectonic areasTranscriptional factorsUnique cognitive abilitiesGene expressionDifferential enlargementDistinct traitsMigratory pathwaysCortical evolutionDecision by division: making cortical maps
Rakic P, Ayoub AE, Breunig JJ, Dominguez MH. Decision by division: making cortical maps. Trends In Neurosciences 2009, 32: 291-301. PMID: 19380167, PMCID: PMC3601545, DOI: 10.1016/j.tins.2009.01.007.Peer-Reviewed Original ResearchConceptsNeuronal fate determinationFate determinationFinal mitotic divisionEvolutionary expansionCell determinationMitotic divisionProtomap hypothesisEarly specificationLatest compendiumBiological basisProliferative zoneNeuronal classesNewborn neuronsBroad spectrumDivisionGenesHuman neocortexCortical malformationsNeuronsRadial unitsCompendiumMigrationCerebral wall
1991
Experimental manipulation of cerebral cortical areas in primates
Rakic P. Experimental manipulation of cerebral cortical areas in primates. Philosophical Transactions Of The Royal Society B Biological Sciences 1991, 331: 291-294. PMID: 1677473, DOI: 10.1098/rstb.1991.0019.Peer-Reviewed Original ResearchConceptsSpecies-specific diversityExperimental manipulationEmbryonic developmentPrimate embryosProtomap hypothesisDevelopmental mechanismsCellular eventsMolecular mechanismsNeuronal phenotypeCerebral cortical areasSynaptic architectureHigher brain functionsCell numberCerebral cortexCongenital disorderExtrinsic influencesSynaptic circuitryCortical areasCytoarchitectonic patternCytoarchitectonic areasBrain functionEmbryosDiversityDistinct areasPhenotypeA novel cytoarchitectonic area induced experimentally within the primate visual cortex.
Rakic P, Suñer I, Williams R. A novel cytoarchitectonic area induced experimentally within the primate visual cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 2083-2087. PMID: 2006147, PMCID: PMC51173, DOI: 10.1073/pnas.88.6.2083.Peer-Reviewed Original ResearchConceptsArea 17Cytoarchitectonic areasVisual cortexSecondary visual cortexPrimary visual cortexPrimate visual cortexAfferent fibersCerebral cortexCortical neuronsThalamic inputsCortical connectionsThalamic fibersCytoarchitectonic regionsCortexCortical parcellationAberrant combinationsArea XProtomap hypothesisCell-cell interactionsNeurons