2001
Normal Programmed Cell Death of Developing Avian and Mammalian Neurons Following Inhibition or Genetic Deletion of Caspases
Oppenheim R, Kuan C, Prevette D, Rakic P, Yaginuma H. Normal Programmed Cell Death of Developing Avian and Mammalian Neurons Following Inhibition or Genetic Deletion of Caspases. Research And Perspectives In Neurosciences 2001, 61-74. DOI: 10.1007/978-3-662-04333-2_6.Peer-Reviewed Original ResearchCell deathAbsence of caspasesProgrammed Cell DeathCaspase family membersPost-mitotic neuronsGenetic deletionCaspase inhibitorsCaspase activityNeuronal PCDMammalian neuronsPCDCaspasesChick embryosDeletionFamily membersMorphological degenerationEmbryosUpstreamNeuronsNormal occurrenceInhibitorsOvoInhibitionMembersDeath
2000
Caspase‐3 is required for apoptosis‐associated DNA fragmentation but not for cell death in neurons deprived of potassium
D'Mello S, Kuan C, Flavell R, Rakic P. Caspase‐3 is required for apoptosis‐associated DNA fragmentation but not for cell death in neurons deprived of potassium. Journal Of Neuroscience Research 2000, 59: 24-31. PMID: 10658182, DOI: 10.1002/(sici)1097-4547(20000101)59:1<24::aid-jnr4>3.0.co;2-8.Peer-Reviewed Original ResearchConceptsCell deathCaspase-3Apoptosis-associated DNA fragmentationDNA fragmentationCell death pathwaysRegulated cell deathPan-caspase inhibitorApoptosis-inducing stimuliDeath pathwaysChromatin condensationCaspase inhibitorsCaspase inhibitionApoptotic featuresCerebellar granule neuronsPotassium deprivationFmkCultured cerebellar granule neuronsCaspasesCrucial effectorNonneuronal cellsApoptosisSame extentGranule neuronsPivotal roleNeuronal death