2023
Shared and Distinct Brain Regions Targeted for Immediate Early Gene Expression by Ketamine and Psilocybin
Davoudian P, Shao L, Kwan A. Shared and Distinct Brain Regions Targeted for Immediate Early Gene Expression by Ketamine and Psilocybin. ACS Chemical Neuroscience 2023, 14: 468-480. PMID: 36630309, PMCID: PMC9898239, DOI: 10.1021/acschemneuro.2c00637.Peer-Reviewed Original ResearchConceptsC-fos expressionBrain regionsNeural plasticityPlasticity-related gene expressionPrimary visual cortexNumerous brain regionsAnterior cingulate cortexExact brain regionsContribution of receptorsDistinct brain regionsImmediate early gene expressionDorsal rapheGlutamatergic receptorsCA1 subfieldSubanesthetic ketamineFemale miceLocus coeruleusInsular cortexSaline controlsTherapeutic effectPsilocybin administrationBasolateral amygdalaLateral habenulaCingulate cortexVisual cortex
2018
Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex
Seeman SC, Campagnola L, Davoudian PA, Hoggarth A, Hage TA, Bosma-Moody A, Baker CA, Lee JH, Mihalas S, Teeter C, Ko AL, Ojemann JG, Gwinn RP, Silbergeld DL, Cobbs C, Phillips J, Lein E, Murphy G, Koch C, Zeng H, Jarsky T. Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex. ELife 2018, 7: e37349. PMID: 30256194, PMCID: PMC6158007, DOI: 10.7554/elife.37349.Peer-Reviewed Original ResearchConceptsRecurrent excitatory connectivityExcitatory connectivityAdult mouse primary visual cortexMouse primary visual cortexHuman cortexLayer 2/3 neuronsClasses of neuronsPrimary visual cortexShort-term depressionBody of evidenceExcitatory neuronsAdult miceVisual cortexSynaptic signalingTwo-photon optogeneticsCell classesCortical networksCortical microcircuitsCortexNeuronsFuture studiesMiceMicrocircuitsSynapses