2023
Hospitalisations for heart failure: increased palliative care referrals − a veterans affairs hospital initiative
Gruen J, Gandhi P, Gillespie-Heyman S, Shamas T, Adelman S, Ruskin A, Bauer M, Merchant N. Hospitalisations for heart failure: increased palliative care referrals − a veterans affairs hospital initiative. BMJ Supportive & Palliative Care 2023, 14: e1309-e1316. PMID: 36609533, DOI: 10.1136/spcare-2022-004118.Peer-Reviewed Original ResearchHeart failurePalliative careHF admissionsMedian B-type natriuretic peptideB-type natriuretic peptidePalliative care referralCare educationVeterans Affairs hospitalPercentage of referralsStudy-Act cyclesQuality of lifeMultiple PDSA cyclesPg/mLPC consultHF managementHF patientsBaseline medianCare referralHospital InitiativeReferral guidelinesSignificant morbidityNatriuretic peptideMean ageNew referralsReferral criteria
2016
The Importance of Worsening Heart Failure in Ambulatory Patients Definition, Characteristics, and Effects of Amino-Terminal Pro-B-Type Natriuretic Peptide Guided Therapy
Mallick A, Gandhi PU, Gaggin HK, Ibrahim N, Januzzi JL. The Importance of Worsening Heart Failure in Ambulatory Patients Definition, Characteristics, and Effects of Amino-Terminal Pro-B-Type Natriuretic Peptide Guided Therapy. JACC Heart Failure 2016, 4: 749-755. PMID: 27179830, DOI: 10.1016/j.jchf.2016.03.012.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdrenergic beta-AntagonistsAgedAmbulatory CareAngiotensin-Converting Enzyme InhibitorsCardiovascular DiseasesDisease ProgressionFemaleHeart FailureHospitalizationHumansMaleMiddle AgedMineralocorticoid Receptor AntagonistsNatriuretic Peptide, BrainPatient Care PlanningPeptide FragmentsProportional Hazards ModelsSodium Potassium Chloride Symporter InhibitorsStandard of CareTreatment OutcomeConceptsHeart failureChronic HFrEFNT-proBNPEjection fractionN-terminal pro-B-type natriuretic peptide concentrationsHigher loop diuretic dosesAngiotensin-converting enzyme inhibitorB-type natriuretic peptideAmbulatory heart failureAmino-Terminal ProJugular venous distensionLoop diuretic dosesAcute heart failureDecompensated heart failureReduced ejection fractionEvent-free survivalNatriuretic peptide concentrationsHigher ejection fractionStandard of careRelevant clinical eventsDiuretic therapyHF managementCardiovascular deathDiuretic dosesVenous distension
2014
Characterization and Prediction of Adverse Events From Intensive Chronic Heart Failure Management and Effect on Quality of Life: Results From the Pro-B-Type Natriuretic Peptide Outpatient-Tailored Chronic Heart Failure Therapy (PROTECT) Study
Gandhi PU, Szymonifka J, Motiwala SR, Belcher AM, Januzzi JL, Gaggin HK. Characterization and Prediction of Adverse Events From Intensive Chronic Heart Failure Management and Effect on Quality of Life: Results From the Pro-B-Type Natriuretic Peptide Outpatient-Tailored Chronic Heart Failure Therapy (PROTECT) Study. Journal Of Cardiac Failure 2014, 21: 9-15. PMID: 25463415, DOI: 10.1016/j.cardfail.2014.10.008.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiomarkersCardiovascular AgentsChronic DiseaseDisease ManagementDizzinessFemaleHeart FailureHumansMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsPredictive Value of TestsProspective StudiesQuality of LifeRenal InsufficiencySurveys and QuestionnairesTreatment OutcomeConceptsTreatment-related serious adverse eventsSerious adverse eventsQuality of lifeAdverse eventsRisk scoreN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideChronic heart failure managementHeart Failure Questionnaire scoreWorse QOLAcute renal failureFirst cardiovascular eventHeart failure managementHeart failure therapyWorse functional classHighest-risk quartileCare armHF careHF managementSystolic HFCardiovascular eventsNT-proBNPReverse remodelingFailure therapyRenal failure