2015
Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure
Gandhi PU, Gaggin HK, Belcher AM, Harisiades JE, Basile A, Falco A, Rosati A, Piscione F, Januzzi JL, Turco MC. Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure. Clinica Chimica Acta 2015, 445: 73-78. PMID: 25753466, DOI: 10.1016/j.cca.2015.02.048.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdaptor Proteins, Signal TransducingAdrenomedullinAgedAged, 80 and overApoptosis Regulatory ProteinsAtrial Natriuretic FactorBiomarkersErbB ReceptorsFemaleGene ExpressionHeart FailureHeart VentriclesHumansInterleukin-1 Receptor-Like 1 ProteinKidney Function TestsMalePrognosisReceptors, Cell SurfaceStroke VolumeSurvival AnalysisConceptsLeft ventricular ejection fractionBcl-2-associated athanogene 3Heart failureNatriuretic peptidePlasma concentrationsCox proportional hazards regressionWorse renal functionVentricular ejection fractionKaplan-Meier analysisProportional hazards regressionSignificant mortality predictorsCox proportional hazardsGenesis of cardiomyopathyHF prognosisHF patientsBaseline characteristicsPrimary endpointRenal functionEjection fractionHazards regressionMortality predictorsVital statusPrognostic valuePatientsProportional hazards
2014
Clinical Impact of Atrial Fibrillation in Patients With the HeartMate II Left Ventricular Assist Device
Enriquez AD, Calenda B, Gandhi PU, Nair AP, Anyanwu AC, Pinney SP. Clinical Impact of Atrial Fibrillation in Patients With the HeartMate II Left Ventricular Assist Device. Journal Of The American College Of Cardiology 2014, 64: 1883-1890. PMID: 25444141, DOI: 10.1016/j.jacc.2014.07.989.Peer-Reviewed Original ResearchConceptsParoxysmal atrial fibrillationAtrial fibrillationHF hospitalizationThromboembolic eventsVentricular assist deviceHeartMate IIHMII LVADAssist deviceImpact of AFCox proportional hazards regressionEffect of AFKaplan-Meier survival analysisHigh INR levelsHeart failure hospitalizationMajor bleeding eventsPersistent atrial fibrillationProportional hazards regressionBleeding eventsHMII implantationINR levelsFailure hospitalizationPatient yearsComposite endpointIndependent predictorsClinical outcomes