Altered neuronal excitability in a Hodgkin-Huxley model incorporating channelopathies of the delayed rectifier potassium channel
Hafez O, Gottschalk A. Altered neuronal excitability in a Hodgkin-Huxley model incorporating channelopathies of the delayed rectifier potassium channel. Journal Of Computational Neuroscience 2020, 48: 377-386. PMID: 33063225, DOI: 10.1007/s10827-020-00766-1.Peer-Reviewed Original ResearchConceptsRectifying K+ channelsDelayed rectifier K+ channelsNeuronal excitabilityK+ channelsEnhanced neuronal excitabilityK+ channels Kv1.1HH modelKv1.1 channelsChannelopathiesHodgkin-HuxleyHodgkin-Huxley (HH) modelNeural excitabilityMaximal conductanceVoltage sensitivityKv1.1Hodgkin-Huxley modelModify excitabilityRate of activationNeural activityGenetic modificationModel of neural excitation