1989
The Effect of Diazepam on Neonatal Seizure: In Vivo 31P and 1H NMR Study
Young R, Chen B, Petroff O, Gore J, Cowan B, Novotny E, Wong M, Zuckerman K. The Effect of Diazepam on Neonatal Seizure: In Vivo 31P and 1H NMR Study. Pediatric Research 1989, 25: 27-31. PMID: 2919113, DOI: 10.1203/00006450-198901000-00006.Peer-Reviewed Original ResearchConceptsBrain lactateBrain high-energy phosphatesArrest of seizuresFlurothyl-induced seizuresCerebral blood flowNormalization of EEGEffects of diazepamVivo 31P nuclear magnetic resonance spectroscopyHigh-energy phosphatesElectrographic seizuresNeonatal seizuresNeonatal dogsPostictal periodBrain pHBaseline valuesBlood flowBrain phosphocreatineMetabolic recoveryProlonged elevationSeizuresSustained increaseVivo 31PRapid returnDiazepamEnergy phosphates
1988
Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain.
C. Petroff O, Prichard J, Ogino T, Shulman R. Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain. Neurology 1988, 38: 1569-74. PMID: 3419601, DOI: 10.1212/wnl.38.10.1569.Peer-Reviewed Original ResearchConceptsBlood glucoseCerebral lactate accumulationLactate accumulationProton magnetic resonance spectroscopic studyWet weight/minCerebral metabolismCardiac arrestControl rabbitsRabbit brainGlycolytic rateMagnetic resonance spectroscopic measurementsCarbohydrate metabolismEquivalents/RabbitsMagnetic resonance spectroscopyMetabolismGlucoseCarbohydrate availabilityGlucose equivalent/