2013
Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases
Karagkounis G, Torbenson MS, Daniel HD, Azad NS, Diaz LA, Donehower RC, Hirose K, Ahuja N, Pawlik TM, Choti MA. Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases. Cancer 2013, 119: 4137-4144. PMID: 24104864, PMCID: PMC3967132, DOI: 10.1002/cncr.28347.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesSurgical therapyBRAF mutationsLiver metastasesKRAS statusPrognostic impactKRAS mutationsMolecular biomarkersThird of patientsRecurrence-free survivalKRAS gene mutationsPrognostic determinantsColorectal metastasesSurgical cohortWorse survivalClinicopathologic factorsIndependent predictorsCancer surgeryClinicopathologic featuresTumor numberPrognostic significanceBRAF analysisColorectal cancerLiver surgeryLower incidence
2008
Management of Retroperitoneal Sarcomas
Hueman MT, Herman JM, Ahuja N. Management of Retroperitoneal Sarcomas. Surgical Clinics Of North America 2008, 88: 583-597. PMID: 18514700, DOI: 10.1016/j.suc.2008.03.002.Peer-Reviewed Original ResearchConceptsRetroperitoneal sarcomaLocal recurrenceMorbidity of therapyDistant metastatic diseaseAggressive surgical approachCurative treatment optionManagement of patientsHigh-grade lesionsMetastatic diseaseSurgical therapyTherapeutic challengeSurgical approachTreatment optionsExtent of invasionDisease controlSarcomaCommon typePatientsRecurrenceTherapyMorbidityLesionsManagementDiseaseDiagnosis