2005
Sleep, breathing, and menopause: The effect of fluctuating estrogen and progesterone on sleep and breathing in women
D'Ambrosio C, Stachenfeld NS, Pisani M, Mohsenin V. Sleep, breathing, and menopause: The effect of fluctuating estrogen and progesterone on sleep and breathing in women. Gender Medicine 2005, 2: 238-245. PMID: 16464735, DOI: 10.1016/s1550-8579(05)80053-1.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingSex hormone deficiencyObstructive sleep apneaLA administrationHormone deficiencyLeuprolide acetateSleep fragmentationDevelopment of OSADevelopment of SDBSignificant sleep-disordered breathingGonadotropin-releasing hormone analogueApnea-hypopnea indexUpper airway resistanceCessation of mensesAdministration of estrogenHours of sleepClimacteric vasomotor symptomsPolysomnographic evaluationVasomotor symptomsClimacteric symptomsMenopausal levelsDaily administrationHealthy womenSleep apneaArousal index
2003
Oestrogen effects on urine concentrating response in young women
Stachenfeld NS, Taylor HS, Leone CA, Keefe DL. Oestrogen effects on urine concentrating response in young women. The Journal Of Physiology 2003, 552: 869-880. PMID: 12923212, PMCID: PMC2343447, DOI: 10.1113/jphysiol.2003.046920.Peer-Reviewed Original ResearchConceptsAVP infusionRenal sensitivityHormone treatmentDistal tubular sodium reabsorptionRenal free water clearanceRenal fluid retentionTubular sodium reabsorptionFree water clearancePlasma AVP concentrationArginine vasopressin releaseRate of clearancePhysiological rangeOE2 treatmentSodium excretionGnRHa administrationSodium reabsorptionEstrogen effectsEstrogen treatmentFluid retentionLeuprolide acetateWater clearanceRenal waterAVP concentrationVasopressin releaseUrine osmolality
2002
Estrogen effects on osmotic regulation of AVP and fluid balance
Stachenfeld NS, Keefe DL. Estrogen effects on osmotic regulation of AVP and fluid balance. AJP Endocrinology And Metabolism 2002, 283: e711-e721. PMID: 12217888, DOI: 10.1152/ajpendo.00192.2002.Peer-Reviewed Original ResearchConceptsHormone treatmentEstrogen effectsPlasma renin activityFree water clearanceEnd of recoveryIntrarenal effectsRenal sensitivityRenin activitySodium excretionFractional excretionAVP increaseSodium retentionFluid retentionLeuprolide acetateWater clearanceEndogenous estrogensAldosterone stimulationFluid balanceGnRHaNaCl infusionPg/EstrogenAVPProgesteroneExcretion