2019
Localising movement disorders in childhood
Bamford NS, McVicar K. Localising movement disorders in childhood. The Lancet Child & Adolescent Health 2019, 3: 917-928. PMID: 31653548, PMCID: PMC7102738, DOI: 10.1016/s2352-4642(19)30330-x.Peer-Reviewed Original ResearchConceptsMovement disordersBasal gangliaBasal ganglia functionMajor movement disordersGanglia functionNew pharmacologicalTreatment decisionsClinical definitionSynaptic functionElectrophysiological approachesDisordersMotor learningGangliaChildrenIon channelsThalamusCortexPharmacologicalDiseasePhysiological frameworkDiagnosisNeuronsReceptors
2011
Imaging Presynaptic Exocytosis in Corticostriatal Slices
Wong MY, Sulzer D, Bamford NS. Imaging Presynaptic Exocytosis in Corticostriatal Slices. Methods In Molecular Biology 2011, 793: 363-376. PMID: 21913113, PMCID: PMC6486818, DOI: 10.1007/978-1-61779-328-8_24.Peer-Reviewed Original ResearchConceptsGlutamatergic corticostriatal terminalsCorticostriatal terminalsCorticostriatal slicesSynaptic dysfunctionBrain slicesSynaptic functionNeuropsychiatric disordersNeurodegenerative diseasesChromaffin cellsHuntington's diseaseDiseaseDrug addictionPresynaptic exocytosisFM1-43Synaptic vesicle fusionCell culturesFluorescent endocytic tracersParkinsonismDysfunctionSlices
2010
Chapter 35 Alterations in Corticostriatal Synaptic Function in Huntington's and Parkinson's Diseases
Cepeda C, Bamford N, André V, Levine M. Chapter 35 Alterations in Corticostriatal Synaptic Function in Huntington's and Parkinson's Diseases. Techniques In The Behavioral And Neural Sciences 2010, 20: 607-623. DOI: 10.1016/b978-0-12-374767-9.00035-4.Peer-Reviewed Original ResearchMedium-sized spiny neuronsParkinson's diseaseHuntington's diseaseCorticostriatal pathwayCortico-basal ganglia-thalamocortical loopsCorticostriatal synaptic functionBasal ganglia neuronsVariety of interneuronsGenetic mouse modelsPrincipal cell typesCoordinated preDA neuronsPostsynaptic actionsMotor disturbancesGanglion neuronsSpiny neuronsCortical neuronsElectrophysiological changesMouse modelSynaptic inputsAnimal modelsEventual degenerationSynaptic functionSubsequent degenerationPD model