2024
North–south pathways, emerging variants, and high climate suitability characterize the recent spread of dengue virus serotypes 2 and 3 in the Dominican Republic
Miguel I, Feliz E, Agramonte R, Martinez P, Vergara C, Imbert Y, De la Cruz L, de Castro N, Cedano O, De la Paz Y, Fonseca V, Santiago G, Muñoz-Jordán J, Peguero A, Paulino-Ramírez R, Grubaugh N, de Filippis A, Alcantara L, Rico J, Lourenço J, Franco L, Giovanetti M. North–south pathways, emerging variants, and high climate suitability characterize the recent spread of dengue virus serotypes 2 and 3 in the Dominican Republic. BMC Infectious Diseases 2024, 24: 751. PMID: 39075335, PMCID: PMC11288047, DOI: 10.1186/s12879-024-09658-6.Peer-Reviewed Original ResearchConceptsGenome sequenceCombination of genome sequencingTrace transmission pathwaysDengue virusHistorical climatic patternsHigh climatic suitabilityCo-circulationDengue virus serotype 2Transmission pathwaysPhylogenetic analysisVirus transmission pathwaysBiodiversity hotspotHistorical climate dataVirus lineagesDominican RepublicImpacts of climate changeLineagesClimatic suitabilityClimate dataRising temperaturePathwaySerotype 2Subtropical regionsTransmission dynamicsImpact of climatic factors
2016
Isolation of a Novel Insect-Specific Flavivirus from Culiseta melanura in the Northeastern United States
Misencik MJ, Grubaugh ND, Andreadis TG, Ebel GD, Armstrong PM. Isolation of a Novel Insect-Specific Flavivirus from Culiseta melanura in the Northeastern United States. Vector-Borne And Zoonotic Diseases 2016, 16: 181-190. PMID: 26807512, PMCID: PMC4779966, DOI: 10.1089/vbz.2015.1889.Peer-Reviewed Original ResearchConceptsInsect-specific flavivirusesOpen reading framePhylogenetic analysisDistinct evolutionary lineagesAmino acid sequence identityObvious geographic structureLimited genetic variationNovel insect-specific flavivirusEvolutionary lineagesHost associationsGeographic structureComplete genomeGenetic variationField-collected mosquitoesReading frameMelanura larvaeNucleotide sequenceSequence identityLarval stagesSampled populationsNortheastern United StatesGenus FlavivirusCalbertado virusNS5 geneViral sequences