Methods for Communicating the Impact of Parameter Uncertainty in a Multiple-Strategies Cost-Effectiveness Comparison
Wolff H, Qendri V, Kunst N, Alarid-Escudero F, Coupé V. Methods for Communicating the Impact of Parameter Uncertainty in a Multiple-Strategies Cost-Effectiveness Comparison. Medical Decision Making 2022, 42: 956-968. PMID: 35587181, PMCID: PMC9452448, DOI: 10.1177/0272989x221100112.Peer-Reviewed Original ResearchConceptsCost-effectiveness acceptability curvesCost-effectiveness acceptability frontierCost-effectiveness analysisImpact of uncertaintyAcceptability curvesDecision analytic modelWrong decisionsCost-effectiveness comparisonBenefit curvePolicy makersHeat mapDecision makersPotential lossIntegration of methodsDecisionsIntegration of informationDecision problemMakersOverview of methodsUncertaintyHealth policyType of informationCourse of actionRelevant informationUse toolEmerging Therapies for COVID-19: The Value of Information From More Clinical Trials
Dijk SW, Krijkamp EM, Kunst N, Gross CP, Wong JB, Hunink MGM. Emerging Therapies for COVID-19: The Value of Information From More Clinical Trials. Value In Health 2022, 25: 1268-1280. PMID: 35490085, PMCID: PMC9045876, DOI: 10.1016/j.jval.2022.03.016.Peer-Reviewed Original ResearchConceptsCohort state-transition modelUS healthcare perspectiveValue of informationFace of uncertaintyQALY willingnessPolicy makersLifetime horizonHealthcare perspectiveState transition modelInformation analysisImmediate approvalModel outcomesImplementation decisionsOptimal momentWillingnessPolicyMakersMost valueCOVID-19DecisionsCostHorizonFurther researchAdditional evidenceUncertainty