2024
Making Drug Approval Decisions in the Face of Uncertainty: Cumulative Evidence versus Value of Information
Dijk S, Krijkamp E, Kunst N, Labrecque J, Gross C, Pandit A, Lu C, Visser L, Wong J, Hunink M. Making Drug Approval Decisions in the Face of Uncertainty: Cumulative Evidence versus Value of Information. Medical Decision Making 2024, 44: 512-528. PMID: 38828516, PMCID: PMC11283736, DOI: 10.1177/0272989x241255047.Peer-Reviewed Original ResearchValue-of-informationVOI approachPolicy decisionsValue-of-information analysisSuboptimal resource useEvidence accumulationVOI resultsAdministrative policy decisionsDecision making resultsDecision-making strategiesApproval decisionsPolicy approachesMeta-analysisResearch settingsResource useHealth technology assessmentCrisis responseCase studyPolicyCumulative evidenceResource allocationComplexity of decisionsResearch prioritizationDecisionHealth outcomes
2020
Calculating the Expected Value of Sample Information in Practice: Considerations from 3 Case Studies
Heath A, Kunst N, Jackson C, Strong M, Alarid-Escudero F, Goldhaber-Fiebert JD, Baio G, Menzies NA, Jalal H. Calculating the Expected Value of Sample Information in Practice: Considerations from 3 Case Studies. Medical Decision Making 2020, 40: 314-326. PMID: 32297840, PMCID: PMC7968749, DOI: 10.1177/0272989x20912402.Peer-Reviewed Original ResearchConceptsHealth economic modelApproximation methodEconomic modelTraditional Monte Carlo methodTraditional Monte CarloMonte Carlo algorithmMonte Carlo methodHigh computational burdenSample informationCarlo algorithmData generation processCarlo methodMonte CarloComputational burdenComputational speedPolicy decisionsComplex decision modelsComputation methodDecision modelRealistic exampleSample sizeEVSIDifferent examplesExpected valuesCarlo