2022
Emerging Therapies for COVID-19: The Value of Information From More Clinical Trials
Dijk SW, Krijkamp EM, Kunst N, Gross CP, Wong JB, Hunink MGM. Emerging Therapies for COVID-19: The Value of Information From More Clinical Trials. Value In Health 2022, 25: 1268-1280. PMID: 35490085, PMCID: PMC9045876, DOI: 10.1016/j.jval.2022.03.016.Peer-Reviewed Original ResearchConceptsCohort state-transition modelUS healthcare perspectiveValue of informationFace of uncertaintyQALY willingnessPolicy makersLifetime horizonHealthcare perspectiveState transition modelInformation analysisImmediate approvalModel outcomesImplementation decisionsOptimal momentWillingnessPolicyMakersMost valueCOVID-19DecisionsCostHorizonFurther researchAdditional evidenceUncertainty
2021
Cost-Effectiveness of Nivolumab Plus Ipilimumab With and Without Chemotherapy for Advanced Non-Small Cell Lung Cancer
Yang SC, Kunst N, Gross CP, Wang JD, Su WC, Wang SY. Cost-Effectiveness of Nivolumab Plus Ipilimumab With and Without Chemotherapy for Advanced Non-Small Cell Lung Cancer. Frontiers In Oncology 2021, 11: 760686. PMID: 34956882, PMCID: PMC8695441, DOI: 10.3389/fonc.2021.760686.Peer-Reviewed Original ResearchNon-small cell lung cancerIncremental cost-effectiveness ratioMetastatic non-small cell lung cancerCell lung cancerHealth care sector perspectivePD-L1Lung cancerAdvanced non-small cell lung cancerPD-L1 expression levelsCycles of chemotherapyProgression-free survivalFirst-line treatmentCost-effectiveness ratioExpression levelsCheckMate 227Overall survivalSubgroup analysisLifetime horizonOutcome dataChemotherapyPatientsIpilimumabNivolumabQALYSector perspective