2024
Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods
Anwar A, Byrne S, Sharma A, Sands S, Wellman A, Redeker N, Yaggi H, Zinchuk A. Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods. Sleep And Breathing 2024, 28: 2005-2015. PMID: 38995327, DOI: 10.1007/s11325-024-03099-w.Peer-Reviewed Original ResearchObstructive sleep apneaPositive airway pressure effectObstructive sleep apnea traitsCPAP effectsCPAP adherencePrimary outcomePurposeContinuous positive airway pressureFunctional Outcomes of Sleep QuestionnaireEffects of CPAPPositive airway pressureAcademic sleep centerObservational cohort studyPrecision medicine approachCPAP dataCPAP efficacyBaseline polysomnographySleep apneaPrimary therapyAirway pressureSleep centerArousal thresholdPatient-centered outcomesPharyngeal collapseSleep qualityCPAP0488 Exploring Study Recruitment Trends in the Acute Post-Stroke Setting
Schwarz J, Masroor K, Radulescu R, Tsang S, Sheth K, Redeker N, Yaggi H, Geer J. 0488 Exploring Study Recruitment Trends in the Acute Post-Stroke Setting. Sleep 2024, 47: a210-a210. DOI: 10.1093/sleep/zsae067.0488.Peer-Reviewed Original ResearchContinuous positive airway pressureObstructive sleep apneaPositive airway pressureAcute ischemic strokeAirway pressureUpper airway closureSleep-disordered breathingYale-New Haven HospitalCerebral blood flowOSA screeningOSA treatmentSleep apneaImpact cerebral blood flowAcademic medical centerSympathetic activityClinical trialsPatient populationHemodynamic changesRisk factorsPatientsFunctional recoveryExclusion criteriaAirway closureCardiovascular diseaseBlood flow0486 Performing Polysomnography in the Acute Post-stroke Setting
Masroor K, Schwarz J, Radulescu R, Tsang S, Sheth K, Redeker N, Yaggi H, Geer J. 0486 Performing Polysomnography in the Acute Post-stroke Setting. Sleep 2024, 47: a209-a209. DOI: 10.1093/sleep/zsae067.0486.Peer-Reviewed Original ResearchObstructive sleep apneaSleep apneaRates of obstructive sleep apneaSymptoms of obstructive sleep apneaSevere obstructive sleep apneaObstructive sleep apnea diagnosisAcute settingSleep-disordered breathingPercentage of patientsProportion of patientsYale-New Haven HospitalAHI cutoffOSA prevalenceOSA diagnosisPreventing recurrent strokeImprove stroke recoveryPolysomnography testNew Haven HospitalPolysomnographyScreening patientsTherapeutic windowApneaPatientsRisk factorsMedical records0495 Association of Cannabis Use and Symptoms Among Patients with Obstructive Sleep Apnea
Inaya A, Baldassarri S, Sands S, Yaggi H, Wellman A, Redeker N, Zinchuk A. 0495 Association of Cannabis Use and Symptoms Among Patients with Obstructive Sleep Apnea. Sleep 2024, 47: a213-a213. DOI: 10.1093/sleep/zsae067.0495.Peer-Reviewed Original ResearchAssociation of cannabis useCannabis useSleep latencyCannabis usersParticipants self-reported cannabis useLong-term cannabis useLong-term effects of cannabisSelf-reported cannabis useHigh prevalence of painObstructive sleep apneaEffects of cannabisPrevalence of painHigher consumption of alcoholProportion of painNo differenceUsers of cannabisSymptoms of painMann-Whitney U testIncreased sleep latencySleep durationRegular alcohol useSlow wave sleepCPAP effectsOSA severityOSA symptoms
2018
Mechanisms of reduced sleepiness symptoms in heart failure and obstructive sleep apnea
Pak VM, Strouss L, Yaggi HK, Redeker NS, Mohsenin V, Riegel B. Mechanisms of reduced sleepiness symptoms in heart failure and obstructive sleep apnea. Journal Of Sleep Research 2018, 28: e12778. PMID: 30421541, PMCID: PMC6538477, DOI: 10.1111/jsr.12778.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep apneaHeart failureSleepiness symptomsUntreated obstructive sleep apneaHeart failure populationBenefits of treatmentExcessive daytimeEpidemiologic evidenceFailure populationHigh riskApneaClinical practiceCase identificationPatientsSymptomsPossible mechanistic explanationTreatmentFailurePopulationMortalitySleepinessDiseaseSleep
2002
Obstructive Sleep Apnea Syndrome: Its Relationship with Hypertension
Krieger AC, Redeker NS. Obstructive Sleep Apnea Syndrome: Its Relationship with Hypertension. The Journal Of Cardiovascular Nursing 2002, 17: 1-11. PMID: 12358089, DOI: 10.1097/00005082-200210000-00002.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep apneaExcessive cardiovascular morbidityArterial blood pressureDevelopment of hypertensionCardiovascular morbidityBlood pressureClinical evidenceRespiratory disturbancesPrevalent conditionGeneral populationClinical importanceTherapeutic interventionsHypertensionApneaCommon formPossible linkPossible mechanismMorbidityPatientsMortalitySleep