2012
Global Methylation Patterns in Idiopathic Pulmonary Fibrosis
Rabinovich EI, Kapetanaki MG, Steinfeld I, Gibson KF, Pandit KV, Yu G, Yakhini Z, Kaminski N. Global Methylation Patterns in Idiopathic Pulmonary Fibrosis. PLOS ONE 2012, 7: e33770. PMID: 22506007, PMCID: PMC3323629, DOI: 10.1371/journal.pone.0033770.Peer-Reviewed Original ResearchConceptsCpG islandsMethylation patternsEpigenetic changesMethylation profilesHuman CpG island microarrayNuclear element-1 (LINE-1 or L1) retrotransposonsCellular biosynthetic processesCpG island microarrayGlobal methylation profilesRegulation of apoptosisGlobal methylation patternsLung phenotypeBRB-Array ToolsElement-1 (LINE-1 or L1) retrotransposonsCancer-specific changesBiosynthetic processesGlobal hypomethylationSpecific changesExtensive remodelingFalse discovery rateExtracellular matrix depositionArray resultsGenesHypomethylationLung cancer samples
2009
Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data
Corcoran DL, Pandit KV, Gordon B, Bhattacharjee A, Kaminski N, Benos PV. Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data. PLOS ONE 2009, 4: e5279. PMID: 19390574, PMCID: PMC2668758, DOI: 10.1371/journal.pone.0005279.Peer-Reviewed Original ResearchConceptsProtein coding genesMiRNA genesCoding genesIntragenic miRNAsPol II chromatin immunoprecipitationNon-coding RNA regulatorsRNA polymerase II promoterChromatin immunoprecipitation dataDiverse biological processesOwn unique promoterPolymerase II promoterTranscription start siteIntergenic miRNAsTranscription regulationMiRNA promotersRNA regulatorsChromatin immunoprecipitationPromoter organizationHost genesPrimary transcriptTranscript organizationStart siteImmunoprecipitation dataUnique promoterBiological processes