Early-Life Intelligence Predicts Midlife Biological Age
Schaefer JD, Caspi A, Belsky DW, Harrington H, Houts R, Israel S, Levine ME, Sugden K, Williams B, Poulton R, Moffitt TE. Early-Life Intelligence Predicts Midlife Biological Age. The Journals Of Gerontology Series B 2015, 71: 968-977. PMID: 26014827, PMCID: PMC5067943, DOI: 10.1093/geronb/gbv035.Peer-Reviewed Original ResearchConceptsBiological ageEarly-life intelligencePopulation-representative birth cohortNutrition Examination SurveyRates of morbidityMost age-related diseasesAdvanced biological ageHeart ageExamination SurveyAge-related diseasesNational HealthChildhood healthBirth cohortParental socioeconomic statusStudy membersDunedin StudySocioeconomic statusMultiple causesTelomere lengthSignificant predictorsAgeEarly childhoodMortalityMidlifeChildhoodChildhood and later life stressors and increased inflammatory gene expression at older ages
Levine ME, Cole SW, Weir DR, Crimmins EM. Childhood and later life stressors and increased inflammatory gene expression at older ages. Social Science & Medicine 2015, 130: 16-22. PMID: 25658624, PMCID: PMC4394113, DOI: 10.1016/j.socscimed.2015.01.030.Peer-Reviewed Original ResearchConceptsChildhood traumaLow SESPro-inflammatory gene expressionProinflammatory gene expression levelsEarly lifeLater lifeLife health outcomesInflammatory gene expressionLater-life health outcomesHigh riskInflammatory genesAdulthood adversityChildhood healthHealth outcomesAdverse experiencesAdult traumaOlder ageTraumaLate-life stressorsGene expressionElevated levelsFuture healthComposite scoreLife stressorsChildhood