Location-Dependent Excitatory Synaptic Interactions in Pyramidal Neuron Dendrites
Behabadi BF, Polsky A, Jadi M, Schiller J, Mel BW. Location-Dependent Excitatory Synaptic Interactions in Pyramidal Neuron Dendrites. PLOS Computational Biology 2012, 8: e1002599. PMID: 22829759, PMCID: PMC3400572, DOI: 10.1371/journal.pcbi.1002599.Peer-Reviewed Original ResearchConceptsExcitatory synaptic contactsPyramidal neuronsSynaptic contactsSpike thresholdExcitatory synaptic interactionsBasal dendritic arborsNeocortical pyramidal neuronsMore proximal inputsBasal dendritesExcitatory pathwaysDendritic arborsDistal excitationBrain slicesSynaptic projectionsSynaptic interactionsElectrophysiological recordingsProximal inputsResponse modulationFunctional asymmetryNeuronsPeak responseSomaDistal endPN responsesDendrites