2012
Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureus
McAdow M, DeDent AC, Emolo C, Cheng AG, Kreiswirth BN, Missiakas DM, Schneewind O. Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureus. Infection And Immunity 2012, 80: 3389-3398. PMID: 22825443, PMCID: PMC3457572, DOI: 10.1128/iai.00562-12.Peer-Reviewed Original Research
2010
IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge
Kim HK, DeDent A, Cheng AG, McAdow M, Bagnoli F, Missiakas DM, Schneewind O. IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge. Vaccine 2010, 28: 6382-6392. PMID: 20226248, PMCID: PMC3095377, DOI: 10.1016/j.vaccine.2010.02.097.Peer-Reviewed Original ResearchConceptsIntravenous challengeAbscess formationStaphylococcus aureus abscess formationLethal intravenous challengePathogenesis of infectionHospital-acquired infectionsStaphylococcal abscess formationNaïve miceActive immunizationLethal challengeSurface proteinsOpsonophagocytic killingStaphylococcal diseaseFrequent causeSubunit vaccineExperimental animalsMouse bloodAntibodiesStaphylococcus aureusBind hemoglobinVaccineInfectionMiceStaphylococciBacteremia