2024
Sex differences in the acute effects of oral THC: a randomized, placebo-controlled, crossover human laboratory study
Mohammad Aghaei A, Urban Spillane L, Pittman B, Flynn L, De Aquino J, Bassir Nia A, Ranganathan M. Sex differences in the acute effects of oral THC: a randomized, placebo-controlled, crossover human laboratory study. Psychopharmacology 2024, 241: 2145-2155. PMID: 38832949, DOI: 10.1007/s00213-024-06625-6.Peer-Reviewed Original ResearchRey Auditory Verbal Learning TestCannabis use disorderHuman laboratory studiesOral tetrahydrocannabinolPsychoactive effectsSex differencesAuditory Verbal Learning TestDissociative Symptoms ScalePsychotomimetic States InventoryExposure to cannabisVerbal Learning TestPlacebo-controlledIncreased cannabis useInvestigate sex differencesClinician-AdministeredVerbal learningPsychotomimetic effectsCannabinoid effectsLearning TestCannabis useTetrahydrocannabinol dosesEffects of sexUse disorderDose-related effectsIndividual vulnerabilityClinical Outcomes of Intravenous Ketamine Treatment for Depression in the VA Health System.
Pfeiffer P, Geller J, Ganoczy D, Jagusch J, Carty J, Festin F, Gilmer W, Martis B, Ranganathan M, Wiechers I, Hosanagar A. Clinical Outcomes of Intravenous Ketamine Treatment for Depression in the VA Health System. The Journal Of Clinical Psychiatry 2024, 85 PMID: 38206011, DOI: 10.4088/jcp.23m14984.Peer-Reviewed Original ResearchConceptsPHQ-9 scoresKetamine infusionClinical outcomesSymptom improvementInfusion frequencyPatient Health Questionnaire-9 scoreVeterans Health Administration electronic medical recordsBaseline PHQ-9 scoreShort-term clinical trialsAntidepressant medication trialsFirst ketamine infusionIntravenous ketamine treatmentMonths of infusionFrequency of infusionsMinority of patientsVA health systemWeeks of treatmentRoutine clinical practiceMajor depressive disorderNumber of infusionsElectronic medical recordsIntravenous ketamineKetamine treatmentFirst infusionMedication trials
2015
Rapid Changes in Cannabinoid 1 Receptor Availability in Cannabis-Dependent Male Subjects After Abstinence From Cannabis.
D'Souza D, Cortes-Briones J, Ranganathan M, Thurnauer H, Creatura G, Surti T, Planeta B, Neumeister A, Pittman B, Normandin M, Kapinos M, Ropchan J, Huang Y, Carson R, Skosnik P. Rapid Changes in Cannabinoid 1 Receptor Availability in Cannabis-Dependent Male Subjects After Abstinence From Cannabis. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2015, 1: 60-67. PMID: 29560896, DOI: 10.1016/j.bpsc.2015.09.008.Peer-Reviewed Original Research